SCHEMBL9484289

SCHEMBL9484289

O=PCC(c1ccccc1)C(C(=O)c1c(Cl)cccc1Cl)C(=O)c1c(Cl)cccc1Cl

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FEN1 P39748 1/20 0.37
ALDH1A1 P00352 3/20 0.37
KCNQ2 O43526 1/20 0.37
PBRM1 Q86U86 1/20 0.36
CASR P41180 1/20 0.36
GPR55 Q9Y2T6 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HPGD P15428 1/20 0.35
FABP3 P05413 1/20 0.35
FABP4 P15090 1/20 0.35
AKR1B1 P15121 1/20 0.34
CES2 O00748 1/20 0.34
LMNA P02545 1/20 0.34
CES1 P23141 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
P2RX7 Q99572 2/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7182204 0.82 KCNQ2 (0.44) FEN1ALDH1A1KCNQ2PBRM1CASR
SCHEMBL445054 0.79 CA12 (0.45) ALDH1A1L3MBTL1HPGDLMNAMEN1
SCHEMBL6435734 0.77 SLC6A2 (0.42) ALDH1A1TDP1L3MBTL1HPGDLMNA
SCHEMBL7620086 0.77 ALDH1A1 (0.40) FEN1ALDH1A1PBRM1HPGDAKR1B1
SCHEMBL7189380 0.73 KCNQ2 (0.43) FEN1ALDH1A1KCNQ2PBRM1CASR
SCHEMBL7182855 0.73 KCNQ2 (0.43) FEN1KCNQ2L3MBTL1FABP3FABP4
SCHEMBL7189908 0.73 ALDH1A1 (0.42) FEN1ALDH1A1KCNQ2PBRM1CASR
SCHEMBL7183606 0.71 KCNQ2 (0.41) FEN1ALDH1A1KCNQ2PBRM1CASR
SCHEMBL7189082 0.71 KCNQ2 (0.36) FEN1KCNQ2L3MBTL1MEN1KMT2A
SCHEMBL7183493 0.71 L3MBTL1 (0.38) FEN1ALDH1A1KCNQ2PBRM1CASR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5218009-A Photoinitiators for the photopolymerization of ethylenically unsaturated compounds CIBA-GEIGY CORPORATION (US) 1993-06-08 US disclosed