Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 5/20 | 0.57 |
| ▸ | CNR2 | P34972 | 4/20 | 0.55 |
| ▸ | CNR1 | P21554 | 3/20 | 0.55 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.55 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21494376 | 0.81 | HTR1B (0.50) | CNR2CNR1NCEH1CYP2C9GAA | |
| SCHEMBL30726485 | 0.80 | KMT2A (0.53) | NCEH1 | |
| SCHEMBL3406179 | 0.80 | KMT2A (0.53) | NCEH1 | |
| SCHEMBL8084778 | 0.79 | LTB4R (0.69) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL11668948 | 0.79 | LTB4R (0.69) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL10697320 | 0.79 | LTB4R (0.69) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL19160930 | 0.79 | LTB4R (0.69) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL8081137 | 0.79 | LTB4R (0.69) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| Acetic Acid SCHEMBL9452498 | 0.78 | CNR2 (0.58) | CNR2CNR1NCEH1CYP2C9GAA | |
| SCHEMBL2449925 | 0.78 | CNR2 (0.59) | CNR2CNR1CYP2C9GAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527175-A4 | 3-NAPHTHYL-3-CARBOXYALKYLTHIO OR OXY SUBSTITUTED ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | — | 1993-05-05 | — | — | EP | disclosed |
| EP-0527175-A1 | 3-NAPHTHYL-3-CARBOXYALKYLTHIO OR OXY SUBSTITUTED ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-02-17 | — | — | EP | disclosed |
| WO-1991017149-A1 | 3-NAPHTHYL-3-CARBOXYALKYLTHIO OR OXY SUBSTITUTED ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-11-14 | — | — | WO | disclosed |