Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 3/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048106 | 0.87 | MEN1 (0.55) | KMT2AMEN1PTGDR2AKR1B1APEX1 | |
| SCHEMBL9057868 | 0.83 | KMT2A (0.49) | KMT2AMEN1PTGDR2AKR1B1CCR2 | |
| SCHEMBL11263079 | 0.80 | APEX1 (0.70) | KMT2AMEN1PTGDR2APEX1CCR2 | |
| SCHEMBL9049601 | 0.78 | LMNA (0.49) | PTGDR2CCR2MAPT | |
| SCHEMBL9048800 | 0.76 | LMNA (0.51) | KMT2AMEN1PTGDR2AKR1B1APEX1 | |
| SCHEMBL10487926 | 0.74 | MEN1 (0.61) | KMT2AMEN1APEX1MAPT | |
| SCHEMBL9050331 | 0.74 | PTGDR2 (0.42) | KMT2AMEN1PTGDR2AKR1B1CCR2 | |
| SCHEMBL11260208 | 0.73 | APEX1 (0.50) | KMT2AMEN1AKR1B1APEX1CCR2 | |
| SCHEMBL9050224 | 0.72 | LMNA (0.42) | KMT2AMEN1CCR2MAPT | |
| SCHEMBL9047414 | 0.72 | LMNA (0.47) | KMT2ACCR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5234928-A | Inhibit platelet aggregation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0456835-A1 | QUINAZOLINE-3-ALKANOIC ACID DERIVATIVE, SALT THEREOF, AND PRODUCTION THEREOF | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1991-11-21 | — | — | EP | disclosed |