Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CCR2 | P41597 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057868 | 0.91 | KMT2A (0.49) | PTGDR2KMT2AMEN1CCR2ALDH1A1 | |
| SCHEMBL9047414 | 0.82 | LMNA (0.47) | KMT2ACCR2 | |
| SCHEMBL9046149 | 0.82 | AKR1B1 (0.59) | KMT2AMEN1AKR1B10AKR1B1 | |
| SCHEMBL9050224 | 0.80 | LMNA (0.42) | KMT2AMEN1CCR2 | |
| SCHEMBL9049803 | 0.75 | HDAC1 (0.53) | PTGDR2KMT2ATP53AKR1B1 | |
| SCHEMBL9049508 | 0.74 | LMNA (0.43) | CCR2 | |
| SCHEMBL9484457 | 0.74 | KMT2A (0.48) | PTGDR2KMT2AMEN1CCR2AKR1B10 | |
| SCHEMBL9046879 | 0.72 | AKR1B1 (0.55) | AKR1B10AKR1B1 | |
| SCHEMBL9047460 | 0.71 | MEN1 (0.50) | PTGDR2KMT2AMEN1ALDH1A1TP53 | |
| SCHEMBL9049601 | 0.67 | LMNA (0.49) | PTGDR2CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456835-B1 | QUINAZOLINE-3-ALKANOIC ACID DERIVATIVE, SALT THEREOF, AND PRODUCTION THEREOF | KYORIN SEIYAKU KK (JP) | 1996-05-15 | — | — | EP | disclosed |
| EP-0456835-A1 | QUINAZOLINE-3-ALKANOIC ACID DERIVATIVE, SALT THEREOF, AND PRODUCTION THEREOF | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1991-11-21 | — | — | EP | disclosed |