SCHEMBL9485161

SCHEMBL9485161

CN1C(=O)c2cc(Cl)c(Cl)c(Cl)c2C1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 1/20 0.40
HPGD P15428 1/20 0.40
APP P05067 6/20 0.36
CASP3 P42574 1/20 0.35
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
USP2 O75604 1/20 0.34
CASP1 P29466 1/20 0.34
BRCA1 P38398 1/20 0.34
CASP7 P55210 1/20 0.34
LMNA P02545 1/20 0.33
PABPC1 P11940 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9525319 0.78 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDAPPCASP3
SCHEMBL458385 0.78 CYP3A4 (0.35) ALDH1A1CYP3A4GRIN2DGRIN3BGRIN1
SCHEMBL19009043 0.78 ALDH1A1 (0.44) ALDH1A1KDM4EHPGDAPPCASP3
SCHEMBL17303441 0.77 ALDH1A1 (0.38) ALDH1A1KDM4EHPGDAPPCASP3
SCHEMBL8730344 0.77 ALDH1A1 (0.38) ALDH1A1KDM4EHPGDAPPCASP3
SCHEMBL19009047 0.76 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDAPPCASP3
SCHEMBL17193081 0.76 APP (0.38) ALDH1A1KDM4EHPGDAPPCASP3
SCHEMBL6846394 0.76 CYP3A4 (0.30) CYP3A4
SCHEMBL8735799 0.75 CYP3A4 (0.36) ALDH1A1KDM4EHPGDCASP3MEN1
Ethylene SCHEMBL16860553 0.74 CYP3A4 (0.32) ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0525066-A4 PREPARATION OF 3,4,6-TRIFLUOROPHTHALIC ACID 1993-03-17 EP claimed
EP-0525066-A1 PREPARATION OF 3,4,6-TRIFLUOROPHTHALIC ACID. OCCIDENTAL CHEM CO (US) 1993-02-03 EP claimed
WO-1991016308-A1 PREPARATION OF 3,4,6-TRIFLUOROPHTHALIC ACID OCCIDENTAL CHEMICAL CORPORATION (US) 1991-10-31 WO claimed