Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | HTR1F | P30939 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9485928 | 0.85 | HCRTR1 (0.52) | HCRTR1KDM4EALDH1A1KMT2AMAPT | |
| Oxalic Acid SCHEMBL9484406 | 0.82 | HCRTR1 (0.49) | HCRTR1KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL9485102 | 0.79 | HCRTR1 (0.44) | HCRTR1KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL11749690 | 0.78 | HCRTR1 (0.58) | HCRTR1KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL29925789 | 0.77 | HCRTR1 (0.57) | HCRTR1KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL17514133 | 0.77 | HCRTR1 (0.57) | HCRTR1KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL8684224 | 0.77 | KDM4E (0.58) | HCRTR1KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL8785079 | 0.77 | HTR1D (0.62) | ALDH1A1KMT2AMEN1HSD17B10HPGD | |
| SCHEMBL6753577 | 0.77 | MAP2K4 (0.43) | KDM4EALDH1A1HSD17B10MAPK1HPGD | |
| SCHEMBL4901043 | 0.76 | MEN1 (0.57) | KDM4EALDH1A1KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208248-A | Hydroxytryptamine Receptor Agonists | MERCK SHARPE & DOHME, LTD. (GB) | 1993-05-04 | — | — | US | disclosed |
| EP-0494774-A1 | Indazole-substituted fivemembered heteroaromatic compounds | MERCK SHARP & DOHME LTD. (GB) | 1992-07-15 | — | — | EP | disclosed |