Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9270770 | 0.96 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL7939376 | 0.96 | AGTR2 (0.54) | AGTR2 | |
| SCHEMBL9486098 | 0.94 | AGTR2 (0.63) | AGTR2 | |
| SCHEMBL9484924 | 0.93 | AGTR2 (0.60) | AGTR1AGTR2 | |
| SCHEMBL9272898 | 0.93 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL9483971 | 0.93 | EDNRA (0.51) | — | |
| SCHEMBL9131720 | 0.92 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL9489770 | 0.92 | EDNRA (0.49) | — | |
| SCHEMBL9130314 | 0.91 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL9287213 | 0.89 | AGTR1 (0.46) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023399-A1 | 6-AMINO SUBSTITUTED IMIDAZO[4,5-b]PYRIDINES AS ANGIOTENSIN II ANTAGONISTS | MERCK & CO., INC. (US) | 1993-11-25 | — | — | WO | disclosed |
| US-5223499-A | Hypotensive agents | MERCK & CO., INC. (US) | 1993-06-29 | — | — | US | disclosed |