SCHEMBL9485993

SCHEMBL9485993

Nc1ccc(Sc2ccc([S+]([O-])c3ccc(Sc4ccc(N)cc4)cc3)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.64
TSHR P16473 1/20 0.64
MAPK1 P28482 1/20 0.64
MAPT P10636 3/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
PDE7A Q13946 7/20 0.40
ANXA2 P07355 1/20 0.39
S100A10 P60903 1/20 0.39
ALDH1A1 P00352 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
KDM4E B2RXH2 1/20 0.37
KDM1A O60341 1/20 0.36
PDE7B Q9NP56 1/20 0.34
MCL1 Q07820 1/20 0.34
NR1H2 P55055 1/20 0.33
TTBK1 Q5TCY1 1/20 0.33
TTBK2 Q6IQ55 1/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1098379 0.80 CYP3A4 (1.00) CYP3A4TSHRMAPK1MAPTMEN1
SCHEMBL9647870 0.80 CYP3A4 (1.00) CYP3A4TSHRMAPK1MAPTMEN1
SCHEMBL10813732 0.80 CYP3A4 (1.00) CYP3A4TSHRMAPK1MAPTMEN1
SCHEMBL9485438 0.80 CYP3A4 (1.00) CYP3A4TSHRMAPK1MAPTMEN1
SCHEMBL9647766 0.80 CYP3A4 (1.00) CYP3A4TSHRMAPK1MAPTMEN1
SCHEMBL9649049 0.80 CYP3A4 (1.00) CYP3A4TSHRMAPK1MAPTMEN1
SCHEMBL9649030 0.80 CYP3A4 (1.00) CYP3A4TSHRMAPK1MAPTMEN1
SCHEMBL9485453 0.80 CYP3A4 (1.00) CYP3A4TSHRMAPK1MAPTMEN1
4,4'-Thiodianiline SCHEMBL49068 0.80 CYP3A4 (1.00) CYP3A4TSHRMAPK1MAPTMEN1
SCHEMBL9275867 0.79 MAOA (0.45) CYP3A4TSHRMAPK1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0210036-B1 AROMATIC POLY(THIOETHERAMIDE-IMIDES) MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1993-02-10 EP disclosed
EP-0294848-B1 AROMATIC POLYTHIOETHERIMIDE MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1992-03-18 EP disclosed
US-5004800-A Aromatic polythioetherimide MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1991-04-02 US disclosed
EP-0162606-B1 AROMATIC POLYTHIOETHERAMIDES AND PROCESS FOR THEIR PRODUCTION MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1989-01-25 EP disclosed
EP-0294848-A1 Aromatic polythioetherimide MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1988-12-14 EP disclosed
US-4783522-A HEAT RESISTANT MOLDING MATERIALS; AUTOMOBILES, AIRCRAFT, ELECTRONICS MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1988-11-08 US disclosed
US-4724257-A Aromatic polythioetheramide-imide MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1988-02-09 US disclosed
EP-0210036-A2 Aromatic poly(thioetheramide-imides) MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1987-01-28 EP disclosed
US-4621134-A Aromatic polythioetheramide MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1986-11-04 US disclosed
EP-0162606-A1 Aromatic polythioetheramides and process for their production MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1985-11-27 EP disclosed