SCHEMBL9485995

SCHEMBL9485995

Cc1cccc(Oc2cc(C)cc(C)c2C)c1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
GAA P10253 1/20 0.54
L3MBTL1 Q9Y468 2/20 0.49
ACHE P22303 2/20 0.48
AR P10275 3/20 0.45
HTT P42858 3/20 0.42
TDP1 Q9NUW8 1/20 0.42
LMNA P02545 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.40
KMT2A Q03164 2/20 0.40
LYN P07948 1/20 0.40
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
MAPK1 P28482 1/20 0.39
MRGPRX1 Q96LB2 1/20 0.39
MEN1 O00255 1/20 0.39
CASP1 P29466 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9488025 0.85 LTA4H (0.42) ALDH1A1GAAHTTLMNASMN1; SMN2
SCHEMBL9487796 0.83 ALDH1A1 (0.61) ALDH1A1GAAL3MBTL1ACHEAR
SCHEMBL9487744 0.82 ALDH1A1 (0.43) ALDH1A1L3MBTL1TDP1SMN1; SMN2KMT2A
SCHEMBL9486947 0.81 ALDH1A1 (0.58) ALDH1A1GAAL3MBTL1ACHEAR
SCHEMBL12195197 0.81 ALDH1A1 (0.58) ALDH1A1GAAL3MBTL1ACHEAR
SCHEMBL8378002 0.77 ALDH1A1 (0.50) ALDH1A1GAAL3MBTL1ACHEAR
SCHEMBL456868 0.77 ALDH1A1 (0.72) ALDH1A1GAAL3MBTL1ACHEAR
SCHEMBL9487712 0.77 ALDH1A1 (0.41) ALDH1A1GAAL3MBTL1ACHEHTT
SCHEMBL29398372 0.77 ALDH1A1 (0.72) ALDH1A1GAAL3MBTL1ACHEAR
SCHEMBL29746015 0.77 ALDH1A1 (0.72) ALDH1A1GAAL3MBTL1ACHEAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5250657-A Process for preparing polyarylene thioether SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) 1993-10-05 US disclosed
EP-0440106-A2 Process for preparing polyarylene thioethers SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) 1991-08-07 EP disclosed