Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7011158 | 0.87 | MEN1 (0.39) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9486032 | 0.79 | RAB9A (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL23755005 | 0.71 | PTGS1 (0.53) | PTGS1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9485160 | 0.70 | LRRK2 (0.42) | PTGDR2SMN1; SMN2ELANEHDAC7ALDH1A1 | |
| SCHEMBL7015535 | 0.68 | ALDH1A1 (0.45) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL23754873 | 0.68 | PTGS1 (0.58) | PTGS1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL3005820 | 0.67 | ELANE (0.52) | PTGDR2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9485930 | 0.66 | TDP1 (0.40) | PTGDR2CHRM3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8056200 | 0.66 | ELANE (0.50) | PTGDR2NPC1RAB9ASMN1; SMN2MEN1 | |
| Hydrogen Sulfide SCHEMBL27603601 | 0.66 | ELANE (0.50) | PTGDR2NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5243054-A | Hypotensive agents, cardiovascular disorders or nervous system disorders | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-07 | — | — | US | disclosed |