Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 6/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9484754 | 0.99 | RAB9A (0.36) | RAB9ACRBNTHRBNPC1LMNA | |
| SCHEMBL9486091 | 0.99 | RAB9A (0.36) | RAB9ACRBNTHRBNPC1LMNA | |
| SCHEMBL9486166 | 0.99 | RAB9A (0.36) | RAB9ACRBNTHRBNPC1LMNA | |
| SCHEMBL9484886 | 0.99 | RAB9A (0.36) | RAB9ACRBNTHRBNPC1LMNA | |
| SCHEMBL9486631 | 0.99 | RAB9A (0.36) | RAB9ACRBNTHRBNPC1LMNA | |
| SCHEMBL9484845 | 0.99 | RAB9A (0.36) | RAB9ACRBNTHRBNPC1LMNA | |
| SCHEMBL9486170 | 0.99 | RAB9A (0.36) | RAB9ACRBNTHRBNPC1LMNA | |
| SCHEMBL9487280 | 0.98 | RAB9A (0.37) | RAB9ACRBNTHRBFAAHGRM2 | |
| SCHEMBL9485952 | 0.95 | RAB9A (0.33) | RAB9ACRBNCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9491249 | 0.92 | ACACB (0.34) | RAB9ATHRBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343487-B1 | CYCLOHEXYL ESTERS OF ALPHA-FLUORO/CARBOXYLIC ACIDS | F. HOFFMANN-LA ROCHE AG (CH) | 1993-01-20 | — | — | EP | disclosed |