Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.33 |
| ▸ | RELA | Q04206 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 6/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9484754 | 1.00 | RAB9A (0.36) | RAB9ATHRBLMNANPC1NFKB1 | |
| SCHEMBL9486166 | 1.00 | RAB9A (0.36) | RAB9ATHRBLMNANPC1NFKB1 | |
| SCHEMBL9484845 | 1.00 | RAB9A (0.36) | RAB9ATHRBLMNANPC1NFKB1 | |
| SCHEMBL9484886 | 1.00 | RAB9A (0.36) | RAB9ATHRBLMNANPC1NFKB1 | |
| SCHEMBL9486631 | 1.00 | RAB9A (0.36) | RAB9ATHRBLMNANPC1NFKB1 | |
| SCHEMBL9486091 | 1.00 | RAB9A (0.36) | RAB9ATHRBLMNANPC1NFKB1 | |
| SCHEMBL9486105 | 0.99 | RAB9A (0.36) | RAB9ATHRBLMNANPC1NFKB1 | |
| SCHEMBL9487280 | 0.97 | RAB9A (0.37) | RAB9ATHRBCRBNFAAH | |
| SCHEMBL9485952 | 0.94 | RAB9A (0.33) | RAB9ACRBNCYP3A4CYP1A2CYP2C9 | |
| SCHEMBL9491241 | 0.92 | ACACB (0.34) | RAB9ATHRBSMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343487-B1 | CYCLOHEXYL ESTERS OF ALPHA-FLUORO/CARBOXYLIC ACIDS | F. HOFFMANN-LA ROCHE AG (CH) | 1993-01-20 | — | — | EP | disclosed |