Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.42 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.42 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047439 | 0.84 | OXER1 (0.48) | CHRM2HTR1ADRD3SLC6A3KCNH2 | |
| SCHEMBL9487366 | 0.80 | PLA2G4A (0.47) | PLA2G4ACHRM2HTR1ADRD3SLC6A3 | |
| Fumaric Acid SCHEMBL9485587 | 0.80 | ESR1 (0.59) | CHRM2HTR1ADRD3SLC6A3KCNH2 | |
| Fumaric Acid SCHEMBL9485596 | 0.80 | ESR1 (0.59) | CHRM2HTR1ADRD3SLC6A3KCNH2 | |
| Oxalic Acid SCHEMBL9486144 | 0.80 | CHRM2 (0.43) | CHRM2HTR1ADRD3SLC6A3KCNH2 | |
| Hydrochloric Acid SCHEMBL9486579 | 0.79 | BCHE (0.46) | — | |
| Hydrochloric Acid SCHEMBL9486674 | 0.74 | CNR2 (0.50) | CHRM2HTR1ADRD3SLC6A3KCNH2 | |
| SCHEMBL9486172 | 0.73 | CHRM2 (0.47) | CHRM2HTR1ADRD3SLC6A3KCNH2 | |
| SCHEMBL31505225 | 0.73 | ESR1 (0.72) | CHRM2HTR1ADRD3SLC6A3KCNH2 | |
| SCHEMBL282404 | 0.73 | ESR1 (0.72) | CHRM2HTR1ADRD3SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223510-A | ALKYLAMINOALKYL DERIVATIVES OF BENZOFURAN, BENZOTHIOPHENE, INDOLE AND INDOLIZINE, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SANOFI (FR) | 1993-06-29 | — | — | US | disclosed |