SCHEMBL8155771

SCHEMBL8155771

C1=CC2CC3C(CCCC3C3CCCC4C5C=CC=CC5CC43)C2C=C1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EPAS1 Q99814 1/20 0.36
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6911299 0.84 EPAS1 (0.33) EPAS1
SCHEMBL1653614 0.79 ALDH1A1 (0.33) EPAS1ALDH1A1
SCHEMBL9486149 0.76 EPAS1 (0.47) EPAS1
SCHEMBL4623146 0.76 EPAS1 (0.56) EPAS1ALDH1A1
SCHEMBL8147763 0.72
SCHEMBL7530985 0.70 EPAS1 (0.32) EPAS1
SCHEMBL6263752 0.65 EPAS1 (0.37) EPAS1
SCHEMBL22037 0.65
SCHEMBL14534464 0.65
SCHEMBL6453898 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0716092-B1 Organic transition metal compound and process for the preparation of polyolefin using same TOSOH CORP (JP) 2000-10-25 EP disclosed
US-5770666-A METALLOCENE TOSOH CORPORATION (JP) 1998-06-23 US disclosed
EP-0716092-A1 Organic transition metal compound and process for the preparation of polyolefin using same TOSOH CORPORATION (JP) 1996-06-12 EP disclosed