Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12487642 | 0.80 | NPC1 (0.68) | NPC1MAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL18012070 | 0.79 | NPC1 (0.85) | NPC1MAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL289081 | 0.76 | NPC1 (1.00) | NPC1MAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL1984774 | 0.74 | SERPINH1 (0.54) | MAPTSMN1; SMN2KMT2ARAB9AL3MBTL1 | |
| SCHEMBL17470177 | 0.74 | SERPINH1 (0.54) | MAPTSMN1; SMN2KMT2ARAB9AL3MBTL1 | |
| SCHEMBL17997090 | 0.73 | NPC1 (0.73) | NPC1MAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL17997089 | 0.73 | NPC1 (0.77) | NPC1MAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL16541098 | 0.72 | RAB9A (1.00) | NPC1MAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL588963 | 0.72 | KMT2A (0.71) | NPC1MAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL12325869 | 0.71 | NPC1 (0.74) | NPC1MAPTSMN1; SMN2KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223510-A | ALKYLAMINOALKYL DERIVATIVES OF BENZOFURAN, BENZOTHIOPHENE, INDOLE AND INDOLIZINE, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SANOFI (FR) | 1993-06-29 | — | — | US | disclosed |