Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18012070 | 0.85 | NPC1 (0.85) | NPC1SMN1; SMN2MAPTKMT2ARAB9A | |
| SCHEMBL289081 | 0.81 | NPC1 (1.00) | NPC1SMN1; SMN2MAPTKMT2ARAB9A | |
| SCHEMBL9486158 | 0.80 | NPC1 (0.60) | NPC1SMN1; SMN2MAPTKMT2ARAB9A | |
| SCHEMBL9486597 | 0.79 | HTT (0.87) | NPC1SMN1; SMN2MAPTKMT2ARAB9A | |
| SCHEMBL9486652 | 0.78 | HTT (0.64) | NPC1SMN1; SMN2MAPTKMT2ARAB9A | |
| SCHEMBL17997089 | 0.78 | NPC1 (0.77) | NPC1SMN1; SMN2MAPTKMT2ARAB9A | |
| SCHEMBL7780381 | 0.77 | NPSR1 (0.70) | NPC1SMN1; SMN2MAPTKMT2AMAPK1 | |
| SCHEMBL3764481 | 0.77 | MAPK1 (0.70) | NPC1SMN1; SMN2MAPTKMT2AL3MBTL1 | |
| SCHEMBL11850324 | 0.77 | MAPK1 (0.70) | NPC1SMN1; SMN2MAPTKMT2ARAB9A | |
| SCHEMBL16541098 | 0.77 | RAB9A (1.00) | NPC1SMN1; SMN2MAPTKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2581369-A1 | PREPARATION PROCESS OF DRONEDARONE AND ITS SALTS | Jiangsu Hengrui Medicine Co. Ltd. (CN) | 2013-04-17 | — | — | EP | disclosed |
| WO-2012120544-A2 | PROCESS FOR N-[2-n-BUTYL-3-[4-[3-(DI-n-BUTYLAMINO) PROPOXY]ENZOYL]BENZOFURAN-5-YL]METHANESULFONAMIDE HYDROCHLORIDE | SUN PHARMACEUTICAL INDUSTRIES LTD. (IN) | 2012-09-13 | — | — | WO | disclosed |