SCHEMBL9486193

SCHEMBL9486193

O=C(Cl)C(=O)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.76

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.76
ALDH1A1 P00352 2/20 0.70
CES2 O00748 1/20 0.66
CA1 P00915 2/20 0.61
CA2 P00918 2/20 0.61
TDP1 Q9NUW8 2/20 0.61
MAPK1 P28482 2/20 0.59
TSHR P16473 1/20 0.59
SRD5A2 P31213 1/20 0.55
GSK3B P49841 1/20 0.53
LMNA P02545 1/20 0.53
GAA P10253 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.52
POLB P06746 2/20 0.50
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
PHGDH O43175 1/20 0.47
MAPT P10636 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL31718801 0.93 CES1 (0.66) CES1ALDH1A1CES2CA1CA2
SCHEMBL4603989 0.87 CES1 (1.00) CES1ALDH1A1CES2CA1CA2
4-Nitrobenzoyl Chloride SCHEMBL43141 0.83 ALDH1A1 (1.00) CES1ALDH1A1CES2CA1CA2
4-Nitrobenzoyl Chloride SCHEMBL28873526 0.83 ALDH1A1 (1.00) CES1ALDH1A1CES2CA1CA2
SCHEMBL11799262 0.81 CES1 (0.66) CES1ALDH1A1CES2CA1CA2
SCHEMBL11799256 0.81 CES1 (0.66) CES1ALDH1A1CES2CA1CA2
4-Nitrobenzoyl Chloride SCHEMBL5400755 0.81 ALDH1A1 (0.96) CES1ALDH1A1CES2CA1CA2
SCHEMBL15180824 0.81 CES1 (0.79) CES1ALDH1A1CES2CA1CA2
SCHEMBL2099160 0.81 CES1 (0.79) CES1ALDH1A1CES2CA1CA2
SCHEMBL10350330 0.80 ALDH1A1 (0.66) CES1ALDH1A1CES2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117105863-A Two-photon fluorescent probe for rapidly detecting peroxynitrite through lysosome targeting, and preparation method and application thereof 锦州医科大学 2023-11-24 CN claimed
JP-5086096-A None JP disclosed
CN-117105863-A Two-photon fluorescent probe for rapidly detecting peroxynitrite through lysosome targeting, and preparation method and application thereof 锦州医科大学 2023-11-24 CN disclosed
CN-115443134-A Conjugates of cell binding molecules and camptothecin analogs 杭州多禧生物科技有限公司 2022-12-06 CN disclosed
CN-108623611-B Synthesis and application of fluorescent probe for detecting hydrogen peroxide 北京工业大学 2020-09-25 CN disclosed
JP-H0586096-A DIDEOXYNUCLEOTIDE PEPTIDE DERIVATIVE AND ANTI-HIV AGENT CONTAINING THE SAME FUJI YAKUHIN KOGYO KK 1993-04-06 JP disclosed
JP-H00586096-A 0001-01-01 JP disclosed