Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.55 |
| ▸ | AURKA | O14965 | 1/20 | 0.55 |
| ▸ | PRKACA | P17612 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28503928 | 0.89 | RAB9A (0.65) | KDM4ETDP1ALDH1A1MAPTKMT2A | |
| SCHEMBL17866642 | 0.86 | KMT2A (0.67) | KDM4ETDP1ALDH1A1MAPTKMT2A | |
| SCHEMBL9489007 | 0.85 | L3MBTL1 (0.65) | KDM4ETDP1ALDH1A1MAPTKMT2A | |
| SCHEMBL9486988 | 0.85 | KMT2A (0.60) | KDM4ETDP1ALDH1A1MAPTKMT2A | |
| SCHEMBL29736136 | 0.85 | AURKA (0.61) | KDM4ETDP1MAPTKMT2ANPSR1 | |
| SCHEMBL776048 | 0.85 | KDM4E (0.67) | KDM4ETDP1ALDH1A1MAPTKMT2A | |
| SCHEMBL18848512 | 0.84 | NPC1 (0.69) | KDM4ETDP1ALDH1A1MAPTKMT2A | |
| SCHEMBL11972746 | 0.84 | NPC1 (0.74) | KDM4ETDP1ALDH1A1MAPTKMT2A | |
| SCHEMBL12824407 | 0.83 | KDM4E (0.71) | KDM4ETDP1ALDH1A1MAPTKMT2A | |
| SCHEMBL1273826 | 0.83 | KDM4E (0.59) | KDM4ETDP1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250533-A | Fungicidal pyridinylpyrimidines | BAYER AKTIENGESELLSCHAFT (DE) | 1993-10-05 | — | — | US | claimed |
| EP-0431424-A2 | Pyridinylpyrimidin derivatives | BAYER AG (DE) | 1991-06-12 | — | — | EP | claimed |
| JP-5255309-A | — | — | None | — | — | JP | disclosed |
| CN-115340553-A | Pyrimido [1,2-b ] indazole derivative and preparation method and application thereof | 台州市中心医院（台州学院附属医院） | 2022-11-15 | — | — | CN | disclosed |
| US-10930853-B2 | Organic light-emitting device | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-02-23 | — | — | US | disclosed |
| US-20170155048-A1 | ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-06-01 | — | — | US | disclosed |
| JP-H05255309-A | PHENYLPYRIMIDINYLPYRIDINE COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE COMPOUND | FUJI PHOTO FILM CO LTD | 1993-10-05 | — | — | JP | disclosed |
| US-5250533-A | Fungicidal pyridinylpyrimidines | BAYER AKTIENGESELLSCHAFT (DE) | 1993-10-05 | — | — | US | disclosed |
| US-5250533-A | Fungicidal pyridinylpyrimidines | BAYER AKTIENGESELLSCHAFT (DE) | 1993-10-05 | — | — | US | disclosed |
| EP-0431424-A2 | Pyridinylpyrimidin derivatives | BAYER AG (DE) | 1991-06-12 | — | — | EP | disclosed |
| US-4873248-A | Pyridinylpyrimidines having fungicidal activity | SUMITOMO CHEMICAL CO., LTD. (JP) | 1989-10-10 | — | — | US | disclosed |
| EP-0270362-A2 | Pyridinylpyrimidine derivatives, method for production thereof and a fungicide containing them as the active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-06-08 | — | — | EP | disclosed |