SCHEMBL9486972

SCHEMBL9486972

Cc1cc(C)cc(Sc2cc(C)ccc2C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.46
ALDH1A1 P00352 2/20 0.46
JAK2 O60674 1/20 0.46
TP53 P04637 2/20 0.43
HPGD P15428 2/20 0.43
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
GAA P10253 1/20 0.43
ALOX15 P16050 1/20 0.43
ALOX12 P18054 1/20 0.43
KMT2A Q03164 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TUBB4A P04350 2/20 0.40
TUBB P07437 2/20 0.40
TUBA3C P0DPH7 2/20 0.40
TUBA1B P68363 2/20 0.40
TUBA4A P68366 2/20 0.40
TUBB4B P68371 2/20 0.40
TUBB3 Q13509 2/20 0.40
TUBB2A Q13885 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11601099 0.84 MAPT (0.55) MAPTALDH1A1JAK2TP53HPGD
SCHEMBL2728633 0.84 HSD17B10 (0.58) MAPTALDH1A1JAK2TP53HPGD
SCHEMBL29823896 0.84 HSD17B10 (0.58) MAPTALDH1A1JAK2TP53HPGD
SCHEMBL9487673 0.83 HTR1A (0.45) MAPTALDH1A1JAK2TP53HPGD
SCHEMBL9486714 0.81 ALDH1A1 (0.49) MAPTALDH1A1JAK2TP53HPGD
SCHEMBL11947061 0.81 MAPT (0.49) MAPTALDH1A1JAK2TP53HPGD
SCHEMBL14306498 0.78 AR (0.44) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL8374153 0.78 MAPT (0.54) MAPTALDH1A1JAK2TP53HPGD
SCHEMBL12703284 0.77 ALDH1A1 (0.48) MAPTALDH1A1JAK2TP53HPGD
SCHEMBL9488729 0.77 MAPT (0.47) MAPTALDH1A1JAK2TP53HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5250657-A Process for preparing polyarylene thioether SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) 1993-10-05 US disclosed
EP-0440106-A2 Process for preparing polyarylene thioethers SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) 1991-08-07 EP disclosed