Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487116 | 0.81 | SMN1; SMN2 (0.35) | SMN1; SMN2NPSR1KEAP1PKMALDH1A1 | |
| SCHEMBL2675923 | 0.78 | KEAP1 (0.65) | SMN1; SMN2NPSR1KEAP1PKMNPC1 | |
| SCHEMBL30602939 | 0.78 | NPSR1 (0.65) | SMN1; SMN2NPSR1KEAP1PKMNPC1 | |
| SCHEMBL2337609 | 0.78 | NPSR1 (0.65) | SMN1; SMN2NPSR1KEAP1PKMNPC1 | |
| SCHEMBL3659927 | 0.77 | SMN1; SMN2 (0.54) | SMN1; SMN2NPSR1KEAP1PKMNPC1 | |
| SCHEMBL1608822 | 0.74 | SMN1; SMN2 (0.68) | SMN1; SMN2PKMNPC1RAB9AKDM4E | |
| SCHEMBL9480543 | 0.73 | SMN1; SMN2 (0.46) | SMN1; SMN2NPSR1KEAP1PKMNPC1 | |
| SCHEMBL9290493 | 0.73 | SMN1; SMN2 (0.58) | SMN1; SMN2NPSR1KEAP1PKMALDH1A1 | |
| SCHEMBL7867881 | 0.72 | KEAP1 (0.67) | SMN1; SMN2NPSR1KEAP1PKMNPC1 | |
| SCHEMBL30602949 | 0.72 | KEAP1 (0.67) | SMN1; SMN2NPSR1KEAP1PKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346465-B1 | 1-CARBOXY-1-VYNILOXYIMINOAMINOTHIAZOLE CEPHALOSPORING DERIVATIVES AND PROCESS FOR THEIR PREPARATION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-11 | — | — | EP | disclosed |
| US-5084453-A | Antibiotics, bactericides | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| EP-0346465-A1 | 1-CARBOXY-1-VYNILOXYIMINOAMINOTHIAZOLE CEPHALOSPORING DERIVATIVES AND PROCESS FOR THEIR PREPARATION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-12-20 | — | — | EP | disclosed |