Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487121 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2NPSR1KEAP1ALDH1A1CYP1A2 | |
| SCHEMBL1608822 | 0.69 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL18201946 | 0.69 | GAA (0.60) | SMN1; SMN2ALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL2819815 | 0.68 | ALDH1A1 (0.70) | SMN1; SMN2PDK1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9979780 | 0.60 | MAPT (0.46) | NPSR1ALDH1A1HPGDCYP2C19 | |
| SCHEMBL2675923 | 0.59 | KEAP1 (0.65) | SMN1; SMN2NPSR1KEAP1ALDH1A1PKM | |
| SCHEMBL30602939 | 0.59 | NPSR1 (0.65) | SMN1; SMN2NPSR1KEAP1ALDH1A1CYP1A2 | |
| SCHEMBL2337609 | 0.59 | NPSR1 (0.65) | SMN1; SMN2NPSR1KEAP1ALDH1A1CYP1A2 | |
| SCHEMBL2317473 | 0.59 | HTT (0.61) | SMN1; SMN2KEAP1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18618444 | 0.59 | GAA (0.70) | SMN1; SMN2ALDH1A1HPGDALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346465-B1 | 1-CARBOXY-1-VYNILOXYIMINOAMINOTHIAZOLE CEPHALOSPORING DERIVATIVES AND PROCESS FOR THEIR PREPARATION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-11 | — | — | EP | disclosed |
| US-5084453-A | Antibiotics, bactericides | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| EP-0346465-A1 | 1-CARBOXY-1-VYNILOXYIMINOAMINOTHIAZOLE CEPHALOSPORING DERIVATIVES AND PROCESS FOR THEIR PREPARATION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-12-20 | — | — | EP | disclosed |