Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487242 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4EHPGDALOX15 | |
| SCHEMBL15743204 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4EHPGDALOX15 | |
| SCHEMBL9486433 | 0.71 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EHPGDALOX15 | |
| SCHEMBL9486428 | 0.71 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EHPGDALOX15 | |
| SCHEMBL9487845 | 0.71 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EHPGDALOX15 | |
| SCHEMBL9487852 | 0.71 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EHPGDALOX15 | |
| SCHEMBL10875341 | 0.70 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EHPGDALOX15 | |
| Bromide SCHEMBL9487491 | 0.69 | ALDH1A1 (0.49) | ALDH1A1MAPTKDM4EHPGDALOX15 | |
| Bromide SCHEMBL9487486 | 0.69 | ALDH1A1 (0.49) | ALDH1A1MAPTKDM4EHPGDALOX15 | |
| SCHEMBL9388384 | 0.68 | GAA (0.51) | ALDH1A1MAPTKDM4EHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5206375-A | Thiophene derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1993-04-27 | — | — | US | disclosed |