SCHEMBL9487284

SCHEMBL9487284

Cc1cc(Sc2ccc(N)cc2)c(C)cc1Sc1ccc(N)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.56
MAPK1 P28482 2/20 0.56
TSHR P16473 1/20 0.56
PDE7A Q13946 6/20 0.53
HTT P42858 1/20 0.44
PDE7B Q9NP56 1/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 4/20 0.40
ACHE P22303 1/20 0.40
HPGD P15428 3/20 0.40
CYP2C19 P33261 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
KDM4E B2RXH2 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
GAA P10253 1/20 0.40
ALOX15 P16050 1/20 0.40
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31457287 0.87 PDE7A (0.60) CYP3A4MAPK1TSHRPDE7AHTT
SCHEMBL7189836 0.87 PDE7A (0.60) CYP3A4MAPK1TSHRPDE7AHTT
SCHEMBL20854802 0.84 PDE7A (0.52) CYP3A4MAPK1TSHRPDE7AHTT
SCHEMBL7891113 0.79 HPGD (0.53) CYP3A4MAPK1TSHRPDE7AHTT
SCHEMBL18620896 0.78 CYP3A4 (0.52) CYP3A4MAPK1TSHRPDE7AHTT
SCHEMBL10597213 0.76 CYP3A4 (0.61) CYP3A4MAPK1TSHRPDE7AHTT
SCHEMBL11455389 0.76 CYP3A4 (0.61) CYP3A4MAPK1TSHRPDE7AHTT
SCHEMBL5548843 0.75 MAPT (0.57) CYP3A4MAPK1TSHRPDE7AALDH1A1
SCHEMBL29907971 0.74 LMNA (0.43) CYP3A4MAPK1TSHRPDE7AHTT
4,4'-Thiodianiline SCHEMBL49068 0.74 CYP3A4 (1.00) CYP3A4MAPK1TSHRPDE7AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0210036-B1 AROMATIC POLY(THIOETHERAMIDE-IMIDES) MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1993-02-10 EP disclosed
EP-0294848-B1 AROMATIC POLYTHIOETHERIMIDE MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1992-03-18 EP disclosed
US-5004800-A Aromatic polythioetherimide MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1991-04-02 US disclosed
EP-0294848-A1 Aromatic polythioetherimide MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1988-12-14 EP disclosed
US-4783522-A HEAT RESISTANT MOLDING MATERIALS; AUTOMOBILES, AIRCRAFT, ELECTRONICS MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1988-11-08 US disclosed
US-4724257-A Aromatic polythioetheramide-imide MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1988-02-09 US disclosed
EP-0210036-A2 Aromatic poly(thioetheramide-imides) MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1987-01-28 EP disclosed