Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.77 |
| ▸ | HTR2A | P28223 | 1/20 | 0.77 |
| ▸ | HTR2C | P28335 | 1/20 | 0.77 |
| ▸ | HTR2B | P41595 | 1/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.62 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mecoprop SCHEMBL29426474 | 0.87 | TSHR (1.00) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| Mecoprop SCHEMBL11349605 | 0.87 | TSHR (1.00) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| Mecoprop SCHEMBL7762943 | 0.87 | TSHR (1.00) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| Mecoprop SCHEMBL9068516 | 0.87 | TSHR (1.00) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL13092106 | 0.87 | TSHR (0.77) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL10175808 | 0.87 | TSHR (0.77) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| Mecoprop-P SCHEMBL29817687 | 0.87 | TSHR (1.00) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| Mecoprop-P SCHEMBL572351 | 0.87 | TSHR (1.00) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| Mecoprop SCHEMBL54983 | 0.87 | TSHR (1.00) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| Mecoprop SCHEMBL53198 | 0.87 | TSHR (1.00) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262393-B1 | DERIVATIVES OF ARYLOXYCARBONIC ACIDS, THEIR PREPARATION AND THEIR USE | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-01-07 | — | — | EP | disclosed |
| CN-1019485-B | ARYLCARBOXYLIC ACID DERIVATIVE, PREPARATION AND USE THEREOF | SHELL AGRAR GMBH & CO KG (DE) | 1992-12-16 | — | — | CN | disclosed |
| EP-0437640-A1 | Fungicidal amino-thiocarboxylic acid amides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-07-24 | — | — | EP | disclosed |
| EP-0262393-A1 | Derivatives of aryloxycarbonic acids, their preparation and their use | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-04-06 | — | — | EP | disclosed |
| CN-87106006-A | The preparation method of arylcarboxylic acid derivative and application | — | 1988-03-16 | — | — | CN | disclosed |
| US-4645845-A | Novel optically active chroman derivatives, their preparation and novel intermediates | BASF AKTIENGESELLSCHAFT (DE) | 1987-02-24 | — | — | US | disclosed |
| US-4067726-A | 3-Ureido phenylacetamide herbicides | BAYER AKTIENGESELLSCHAFT (DT) | 1978-01-10 | — | — | US | disclosed |