Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.77 |
| ▸ | HTR2A | P28223 | 1/20 | 0.77 |
| ▸ | HTR2C | P28335 | 1/20 | 0.77 |
| ▸ | HTR2B | P41595 | 1/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.62 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13092106 | 1.00 | TSHR (0.77) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| Mecoprop SCHEMBL11349605 | 0.87 | TSHR (1.00) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| Mecoprop-P SCHEMBL29817687 | 0.87 | TSHR (1.00) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL9487387 | 0.87 | TSHR (0.77) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| Mecoprop SCHEMBL54983 | 0.87 | TSHR (1.00) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| Mecoprop SCHEMBL9068516 | 0.87 | TSHR (1.00) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| Mecoprop-P SCHEMBL572351 | 0.87 | TSHR (1.00) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| Mecoprop SCHEMBL29426474 | 0.87 | TSHR (1.00) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| Mecoprop SCHEMBL7762943 | 0.87 | TSHR (1.00) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 | |
| Mecoprop SCHEMBL53198 | 0.87 | TSHR (1.00) | TSHRHTR2AHTR2CHTR2BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130109572-A1 | HERBICIDAL COMPOSITIONS AND METHODS OF USE | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2013-05-02 | — | — | US | disclosed |
| US-20120245213-A1 | HUMAN TYPE I TASTE RECEPTOR SUBUNIT 3 MODULATORS AND METHODS OF USING SAME | MOUNT SINAI SCHOOL OF MEDICINE | 2012-09-27 | — | — | US | disclosed |
| EP-1740039-B1 | Novel herbicide resistance genes | DOW AGROSCIENCES LLC (US) | 2012-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245213-A1 | HUMAN TYPE I TASTE RECEPTOR SUBUNIT 3 MODULATORS AND METHODS OF USING SAME | TAS1R3, TAS2R3, TAS1R1 | TSHR 68/4885HTR2A 118/4885HTR2C 134/4885 |
| US-20130109572-A1 | HERBICIDAL COMPOSITIONS AND METHODS OF USE | DDT, ACHE, CAT | TSHR 3275/4885HTR2A 1351/4885HTR2C 1088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.