Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | ATM | Q13315 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.59 |
| ▸ | MDM4 | O15151 | 1/20 | 0.59 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487596 | 1.00 | POLB (0.66) | POLBATMALDH1A1THRBCYP2C9 | |
| SCHEMBL27761115 | 0.93 | HDAC1 (0.69) | POLBATMALDH1A1THRBCYP2C9 | |
| SCHEMBL10741167 | 0.91 | ALDH1A1 (0.61) | POLBATMALDH1A1THRBCYP2C9 | |
| SCHEMBL27703697 | 0.90 | HDAC1 (0.56) | POLBATMALDH1A1THRBCYP2C9 | |
| SCHEMBL9487303 | 0.89 | TP53 (0.61) | POLBATMALDH1A1GAARAB9A | |
| SCHEMBL9487298 | 0.89 | TP53 (0.61) | POLBATMALDH1A1GAARAB9A | |
| SCHEMBL15290564 | 0.88 | PSMB5 (0.64) | POLBALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL9487603 | 0.88 | POLB (0.67) | POLBATMALDH1A1THRBCYP2C9 | |
| SCHEMBL9487610 | 0.88 | POLB (0.67) | POLBATMALDH1A1THRBCYP2C9 | |
| SCHEMBL13296315 | 0.88 | TACR1 (0.64) | POLBATMALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198397-B1 | METHOD OF PRODUCING L-PHENYLALANINE | KURARAY CO., LTD. (JP) | 1993-01-07 | — | — | EP | disclosed |
| US-4743547-A | PURITY, ENZYME HYDROLYSIS | KURARAY CO., LTD. (JP) | 1988-05-10 | — | — | US | disclosed |
| EP-0198397-A2 | Method of producing L-phenylalanine | KURARAY CO., LTD. (JP) | 1986-10-22 | — | — | EP | disclosed |