Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 6/20 | 0.40 |
| ▸ | PPARA | Q07869 | 5/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 4/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9486984 | 0.93 | MAOA (0.43) | MAOAMAOBPPARGPPARAALOX5 | |
| SCHEMBL28429228 | 0.89 | MAOA (0.48) | MAOAMAOBPPARGPPARAALOX5 | |
| SCHEMBL27826666 | 0.84 | PPARG (0.42) | PPARGPPARAALOX5LMNAPAX8 | |
| SCHEMBL28426970 | 0.82 | MAOA (0.52) | MAOAMAOBLMNAPAX8MTNR1A | |
| SCHEMBL27804824 | 0.79 | LMNA (0.41) | PPARGPPARAALOX5LMNAPAX8 | |
| SCHEMBL11407917 | 0.79 | LMNA (0.41) | PPARGPPARAALOX5LMNAPAX8 | |
| SCHEMBL1455325 | 0.78 | PPARG (0.39) | PPARGPPARAALOX5LMNAPAX8 | |
| SCHEMBL1496802 | 0.77 | MAOA (0.47) | MAOAMAOBPPARGPPARAALOX5 | |
| SCHEMBL8106186 | 0.77 | MAOA (0.47) | MAOAMAOBLMNAMTNR1AMTNR1B | |
| SCHEMBL5968015 | 0.77 | CSNK1E (0.41) | PPARGPPARAALOX5LMNAPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5180852-A | From a disulfide and an alkene, froth flotation agents | PHILLIPS PETROLEUM COMPANY (US) | 1993-01-19 | — | — | US | disclosed |
| US-5132008-A | Froth flotation agents | PHILLIPS PETROLEUM COMPANY (US) | 1992-07-21 | — | — | US | disclosed |