Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 11/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.66 |
| ▸ | PGR | P06401 | 5/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | TNF | P01375 | 1/20 | 0.66 |
| ▸ | IL6 | P05231 | 1/20 | 0.66 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.66 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.66 |
| ▸ | AR | P10275 | 1/20 | 0.66 |
| ▸ | GLUL | P15104 | 1/20 | 0.66 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.66 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487586 | 1.00 | NR3C1 (0.66) | NR3C1HIF1APGRHSD17B10ABCB11 | |
| SCHEMBL10526560 | 1.00 | NR3C1 (0.66) | NR3C1HIF1APGRHSD17B10ABCB11 | |
| SCHEMBL9015066 | 1.00 | NR3C1 (0.66) | NR3C1HIF1APGRHSD17B10ABCB11 | |
| SCHEMBL10526554 | 1.00 | NR3C1 (0.66) | NR3C1HIF1APGRHSD17B10ABCB11 | |
| SCHEMBL9015081 | 1.00 | NR3C1 (0.66) | NR3C1HIF1APGRHSD17B10ABCB11 | |
| SCHEMBL10333733 | 0.90 | PGR (0.63) | NR3C1HIF1APGRHSD17B10ABCB11 | |
| SCHEMBL10333731 | 0.90 | PGR (0.63) | NR3C1HIF1APGRHSD17B10ABCB11 | |
| SCHEMBL10333732 | 0.90 | PGR (0.63) | NR3C1HIF1APGRHSD17B10ABCB11 | |
| SCHEMBL10948193 | 0.87 | PGR (0.61) | NR3C1HIF1APGRHSD17B10ABCB11 | |
| SCHEMBL10948168 | 0.87 | PGR (0.61) | NR3C1HIF1APGRHSD17B10ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5200518-A | Reduced side effcts | KANGWEON NATIONAL UNIVERSITY (KR) | 1993-04-06 | — | — | US | disclosed |
| EP-0503388-A1 | Pregna-21-oic acid esters | TEIKOKU SEIYAKU KABUSHIKI KAISHA (JP) | 1992-09-16 | — | — | EP | disclosed |