Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487796 | 0.86 | ALDH1A1 (0.61) | NPSR1DHFRMAPTKEAP1ALDH1A1 | |
| SCHEMBL5340839 | 0.83 | NPSR1 (0.59) | NPSR1MAPTHPGDALDH1A1GAA | |
| SCHEMBL24576257 | 0.83 | DHFR (0.62) | NPSR1DHFRMAPTHPGDKEAP1 | |
| SCHEMBL11585245 | 0.82 | DHFR (0.57) | NPSR1DHFRMAPTHPGDKEAP1 | |
| SCHEMBL1538371 | 0.80 | MAPT (0.54) | NPSR1DHFRMAPTKEAP1ALDH1A1 | |
| SCHEMBL29377898 | 0.80 | MAPT (0.54) | NPSR1DHFRMAPTKEAP1ALDH1A1 | |
| SCHEMBL9487718 | 0.80 | ALDH1A1 (0.44) | NPSR1DHFRMAPTHPGDKEAP1 | |
| SCHEMBL2339526 | 0.79 | DHFR (0.54) | NPSR1DHFRMAPTHPGDKEAP1 | |
| SCHEMBL30358266 | 0.79 | DHFR (0.54) | NPSR1DHFRMAPTHPGDKEAP1 | |
| SCHEMBL822076 | 0.78 | HTR2A (0.53) | DHFRMAPTKEAP1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250657-A | Process for preparing polyarylene thioether | SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0440106-A2 | Process for preparing polyarylene thioethers | SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) | 1991-08-07 | — | — | EP | disclosed |