Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9488173 | 1.00 | POLB (0.52) | POLBBIRC2PSMB5TACR1TSHR | |
| SCHEMBL8271879 | 0.90 | ITGB3 (0.52) | POLBBIRC2TACR1TSHRTP53 | |
| SCHEMBL9487233 | 0.90 | POLB (0.53) | POLBBIRC2TACR1TSHRTP53 | |
| SCHEMBL9487238 | 0.90 | POLB (0.53) | POLBBIRC2TACR1TSHRTP53 | |
| SCHEMBL27515952 | 0.89 | POLB (0.54) | POLBBIRC2TACR1TSHRTP53 | |
| SCHEMBL10042969 | 0.88 | HDAC1 (0.51) | POLBBIRC2TACR1TSHRTP53 | |
| SCHEMBL9488064 | 0.88 | TACR1 (0.61) | POLBBIRC2TACR1TSHRMEN1 | |
| SCHEMBL9486892 | 0.88 | TACR1 (0.61) | POLBBIRC2TACR1TSHRMEN1 | |
| SCHEMBL9487303 | 0.86 | TP53 (0.61) | POLBPSMB5TACR1TP53MEN1 | |
| SCHEMBL9487298 | 0.86 | TP53 (0.61) | POLBPSMB5TACR1TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198397-B1 | METHOD OF PRODUCING L-PHENYLALANINE | KURARAY CO., LTD. (JP) | 1993-01-07 | — | — | EP | disclosed |
| US-4743547-A | PURITY, ENZYME HYDROLYSIS | KURARAY CO., LTD. (JP) | 1988-05-10 | — | — | US | disclosed |
| EP-0198397-A2 | Method of producing L-phenylalanine | KURARAY CO., LTD. (JP) | 1986-10-22 | — | — | EP | disclosed |