Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9488167 | 0.88 | POLB (0.52) | HDAC1HDAC6POLBBIRC2FAAH | |
| SCHEMBL9488173 | 0.88 | POLB (0.52) | HDAC1HDAC6POLBBIRC2FAAH | |
| SCHEMBL9487233 | 0.86 | POLB (0.53) | POLBBIRC2FAAHTACR1TSHR | |
| SCHEMBL9487238 | 0.86 | POLB (0.53) | POLBBIRC2FAAHTACR1TSHR | |
| SCHEMBL8271879 | 0.86 | ITGB3 (0.52) | POLBBIRC2TACR1TSHRTP53 | |
| SCHEMBL27515952 | 0.85 | POLB (0.54) | POLBBIRC2TACR1TSHRTP53 | |
| SCHEMBL9486892 | 0.84 | TACR1 (0.61) | POLBBIRC2TACR1TSHRMEN1 | |
| SCHEMBL9488064 | 0.84 | TACR1 (0.61) | POLBBIRC2TACR1TSHRMEN1 | |
| SCHEMBL807262 | 0.84 | TSHR (0.50) | POLBBIRC2TSHRALDH1A1GAA | |
| SCHEMBL25034712 | 0.84 | ATM (0.62) | HDAC1HDAC6POLBMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408445-B1 | GOLD(III) COMPLEXES WITH OLIGOPEPTIDES FUNCTIONALIZED WITH SULFUR DONORS AND USE THEREOF AS ANTITUMOR AGENTS | UNIV PADOVA (IT) | 2014-11-19 | — | — | EP | disclosed |
| US-8481496-B2 | Gold (III) complexes with oligopeptides functionalized with sulfur donors and use thereof as antitumor agents | UNIVERSITA' DEGLI STUDI DI PADOVA (IT) | 2013-07-09 | — | — | US | disclosed |
| US-20120101044-A1 | GOLD (III) COMPLEXES WITH OLIGOPEPTIDES FUNCTIONALIZED WITH SULFUR DONORS AND USE THEREOF AS ANTITUMOR AGENTS | UNIVERSITA' DEGLI STUDI DI PADOVA | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101044-A1 | GOLD (III) COMPLEXES WITH OLIGOPEPTIDES FUNCTIONALIZED WITH SULFUR DONORS AND USE THEREOF AS ANTITUMOR AGENTS | UACA, UBXN4, PDIA3 | HDAC1 4189/4885HDAC6 1323/4885HDAC3 2520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.