SCHEMBL9488170

SCHEMBL9488170

CC(c1c[nH]cn1)C(N)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7052027 1.00 SLC7A5 (0.38) SLC7A5
SCHEMBL150490 1.00 SLC7A5 (0.38) SLC7A5
Hydrochloric Acid SCHEMBL9789200 0.98 SLC7A5 (0.36) SLC7A5
SCHEMBL2513127 0.89 SLC7A5 (0.30) SLC7A5
SCHEMBL9489841 0.82
SCHEMBL27765896 0.82 CPB2 (0.31)
SCHEMBL9789201 0.82
SCHEMBL679593 0.81 SLC7A5 (0.33) SLC7A5
SCHEMBL5283576 0.81 SLC7A5 (0.33) SLC7A5
Hydrochloric Acid SCHEMBL9789372 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0338939-B1 HISTAMINE DERIVATIVE, PROCESS FOR HIS PREPARATION AND HIS THERAPEUTIC APPLICATION INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 1993-01-27 EP claimed
EP-0338939-A1 Histamine derivative, process for his preparation and his therapeutic application INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 1989-10-25 EP claimed
US-20210244796-A1 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING AMYLIN AN AMYLIN RECEPTOR AGONIST OR AN AMYLIN ANALOG, AT LEAST ONE IONIC SPECIES AND AN AMPHOIPHILIC COMPOUNDS CONTAINING HYDRIPHOBIC RADICALS ADOCIA (FR) 2021-08-12 US disclosed
EP-3829624-A1 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING AMYLIN, AN AMYLIN RECEPTOR AGONIST OR AN AMYLIN ANALOG, AT LEAST ONE IONIC SPECIES AND AN AMPHIPHILIC COMPOUND CONTAINING HYDROPHOBIC RADICALS Adocia (FR) 2021-06-09 EP disclosed
CN-112805025-A Injectable aqueous composition comprising an amylin, an amylin receptor agonist or an amylin analog, at least one ionic substance and an amphiphilic compound comprising a hydrophobic group 阿道恰公司 2021-05-14 CN disclosed
WO-2020025825-A1 INJECTABLE SOLUTION HAVING PH 7 AND COMPRISING HUMAN GLUCAGON, AT LEAST ONE IONIC SPECIES, AND AN AMPHIPHILIC COMPOUND BEARING HYDROPHOBIC RADICALS ADOCIA (FR) 2020-02-06 WO disclosed
WO-2020025826-A1 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING AMYLIN, AN AMYLIN RECEPTOR AGONIST OR AN AMYLIN ANALOG, AT LEAST ONE IONIC SPECIES AND AN AMPHIPHILIC COMPOUND CONTAINING HYDROPHOBIC RADICALS ADOCIA (FR) 2020-02-06 WO disclosed
WO-2020025824-A1 INJECTABLE SOLUTION AT PH 7, COMPRISING AT LEAST ONE BASAL INSULIN WITH A PI BETWEEN 5.8 AND 8.5, AT LEAST ONE IONIC SPECIES, AND AN AMPHIPHILIC COMPOUND BEARING HYDROPHOBIC RADICALS ADOCIA (FR) 2020-02-06 WO disclosed
CN-101778857-A Platinum (IV) complex compound PLATCO TECHNOLOGIES PROPRIETAR 2010-07-14 CN disclosed
EP-0338939-B1 HISTAMINE DERIVATIVE, PROCESS FOR HIS PREPARATION AND HIS THERAPEUTIC APPLICATION INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 1993-01-27 EP disclosed
EP-0523087-A1 HIGH IMPACT POLYETHYLENE TEREPHTHALATE-POLYCARBONATE BLEND COMPOSITIONS AlliedSignal Inc. (US) 1993-01-20 EP disclosed
US-5034539-A Histamine derivative, process for preparing it and its therapeutic use INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 1991-07-23 US disclosed
EP-0338939-A1 Histamine derivative, process for his preparation and his therapeutic application INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 1989-10-25 EP disclosed
EP-0338939-A1 Histamine derivative, process for his preparation and his therapeutic application INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 1989-10-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210244796-A1 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING AMYLIN AN AMYLIN RECEPTOR AGONIST OR AN AMYLIN ANALOG, AT LEAST ONE IONIC SPECIES AND AN AMPHOIPHILIC COMPOUNDS CONTAINING HYDRIPHOBIC RADICALS GLP1R, IAPP, GPR119 SLC7A5 3408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.