SCHEMBL9488387

SCHEMBL9488387

COS(=O)(=O)c1ccc(Cl)c([N+](=O)[O-])c1

nearest known ligand 0.63

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 18/20 0.63
ALDH1A1 P00352 1/20 0.55
NPBWR1 P48145 1/20 0.54
MCHR1 Q99705 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11589870 0.86 VCAM1 (0.67) VCAM1ALDH1A1NPBWR1MCHR1
SCHEMBL11456478 0.82 ALPL (0.63) VCAM1ALDH1A1
SCHEMBL29196117 0.82 VCAM1 (0.45) VCAM1ALDH1A1NPBWR1MCHR1
SCHEMBL30741202 0.82 VCAM1 (0.45) VCAM1ALDH1A1NPBWR1MCHR1
SCHEMBL9574404 0.81 VCAM1 (0.47) VCAM1ALDH1A1
SCHEMBL30813055 0.81 VCAM1 (0.69) VCAM1ALDH1A1NPBWR1MCHR1
SCHEMBL1097803 0.81 VCAM1 (0.69) VCAM1ALDH1A1NPBWR1MCHR1
SCHEMBL809482 0.80 VCAM1 (0.73) VCAM1ALDH1A1NPBWR1MCHR1
SCHEMBL10452716 0.80 VCAM1 (0.73) VCAM1ALDH1A1NPBWR1MCHR1
SCHEMBL29780388 0.80 VCAM1 (0.73) VCAM1ALDH1A1NPBWR1MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0342532-B1 PROCESS FOR THE PREPARATION OF 4-CHLORO-2-METHYL-5-NITRO-PHENOL Wella Aktiengesellschaft (DE) 1993-01-07 EP claimed
US-4960955-A Process for making 4-chloro-2-methyl-5-nitro-phenol WELLA AKTIENGESELLSCHAFT (DE) 1990-10-02 US disclosed
US-4960955-A Process for making 4-chloro-2-methyl-5-nitro-phenol WELLA AKTIENGESELLSCHAFT (DE) 1990-10-02 US disclosed
EP-0342532-A1 Process for the preparation of 4-chloro-2-methyl-5-nitro-phenol Wella Aktiengesellschaft (DE) 1989-11-23 EP disclosed