Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491235 | 1.00 | POLB (0.42) | POLBGAAHSD17B10ACHELMNA | |
| SCHEMBL9488618 | 0.94 | POLB (0.41) | POLBGAAHSD17B10ACHELMNA | |
| SCHEMBL9488414 | 0.89 | TRPV1 (0.41) | POLBGAAHSD17B10ACHELMNA | |
| SCHEMBL9373011 | 0.86 | TSHR (0.38) | POLBGAAHSD17B10LMNAMAPT | |
| SCHEMBL10469113 | 0.86 | FFAR1 (0.36) | POLBGAAHSD17B10ACHELMNA | |
| SCHEMBL9374981 | 0.86 | MEN1 (0.41) | KMT2AMEN1MTNR1A | |
| SCHEMBL9488354 | 0.85 | — | — | |
| SCHEMBL9372351 | 0.84 | MTNR1A (0.41) | TRPV1MTNR1A | |
| SCHEMBL9490929 | 0.84 | KMT2A (0.43) | POLBGAAHSD17B10KMT2AMEN1 | |
| SCHEMBL9490136 | 0.82 | TRPV1 (0.41) | POLBGAAHSD17B10ACHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337766-B1 | HETERA-ALIPHATIC CARBOXAMIDES | ICI AMERICAS INC. (US) | 1993-03-10 | — | — | EP | disclosed |
| US-5041460-A | Antiallergens, antiinflammatory agents and leukotriene antagonists | ICI AMERICAS INC. (US) | 1991-08-20 | — | — | US | disclosed |
| EP-0337766-A1 | Hetera-aliphatic carboxamides | ICI AMERICAS INC. (US) | 1989-10-18 | — | — | EP | disclosed |