Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9488414 | 0.93 | TRPV1 (0.41) | TRPV1LMNAL3MBTL1ACHEPOLB | |
| SCHEMBL9488618 | 0.88 | POLB (0.41) | TRPV1LMNAL3MBTL1ACHEPOLB | |
| SCHEMBL9488888 | 0.86 | ACACB (0.39) | TRPV1MAPTMTNR1AMTNR1BGPR84 | |
| SCHEMBL9489476 | 0.84 | THRA (0.43) | TRPV1L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL9490127 | 0.84 | MAPT (0.41) | LMNAL3MBTL1GAAKMT2AMEN1 | |
| SCHEMBL9488829 | 0.83 | MEN1 (0.40) | KMT2AMEN1 | |
| SCHEMBL10469189 | 0.83 | GPR84 (0.39) | TRPV1GAAMAPTMTNR1AMTNR1B | |
| SCHEMBL9489892 | 0.83 | KMT2A (0.45) | TRPV1HSD17B10KMT2AMEN1MAPT | |
| SCHEMBL8532689 | 0.83 | GPR84 (0.49) | TRPV1L3MBTL1HSD17B10KMT2AMEN1 | |
| SCHEMBL9488371 | 0.83 | GAA (0.43) | LMNAL3MBTL1ACHEPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337766-B1 | HETERA-ALIPHATIC CARBOXAMIDES | ICI AMERICAS INC. (US) | 1993-03-10 | — | — | EP | disclosed |
| US-5041460-A | Antiallergens, antiinflammatory agents and leukotriene antagonists | ICI AMERICAS INC. (US) | 1991-08-20 | — | — | US | disclosed |
| EP-0337766-A1 | Hetera-aliphatic carboxamides | ICI AMERICAS INC. (US) | 1989-10-18 | — | — | EP | disclosed |