Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 15/20 | 0.43 |
| ▸ | RARG | P13631 | 14/20 | 0.43 |
| ▸ | RARA | P10276 | 12/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 4/20 | 0.36 |
| ▸ | RXRB | P28702 | 2/20 | 0.35 |
| ▸ | RXRG | P48443 | 2/20 | 0.35 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9337039 | 0.84 | RARB (0.40) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL9006875 | 0.82 | RARB (0.64) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL9006999 | 0.82 | RARB (0.49) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL9006972 | 0.77 | RARB (0.40) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL5960214 | 0.76 | RARB (0.35) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL9007075 | 0.76 | RARB (0.49) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL8772593 | 0.75 | RARB (0.45) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL9737688 | 0.73 | RARB (0.39) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL9176637 | 0.72 | RARB (0.64) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL9006881 | 0.71 | RARG (0.35) | RARBRARGRARACYP26A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571546-A1 | CHROMAN AND THIOCHROMANS WITH PHENYLETHYNYL SUBSTITUENTS AT THE 7-POSITION HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY. | ALLERGAN INC (US) | 1993-12-01 | — | — | EP | disclosed |