Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 0.73 |
| ▸ | RAB9A | P51151 | 11/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.73 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | MITF | O75030 | 1/20 | 0.73 |
| ▸ | KDM5A | P29375 | 1/20 | 0.73 |
| ▸ | KDM5C | P41229 | 1/20 | 0.73 |
| ▸ | ALDH1A3 | P47895 | 4/20 | 0.69 |
| ▸ | APP | P05067 | 3/20 | 0.66 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | PKM | P14618 | 4/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.62 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1691812 | 0.98 | NPC1 (0.71) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6320343 | 0.98 | ALDH1A3 (0.72) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2128252 | 0.91 | APP (0.74) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4954009 | 0.87 | ALDH1A3 (0.88) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4952001 | 0.87 | ALDH1A3 (0.78) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL396368 | 0.85 | NPC1 (1.00) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2431086 | 0.83 | ALDH1A3 (0.68) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2427884 | 0.83 | ALDH1A3 (0.68) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2429882 | 0.83 | ALDH1A3 (0.68) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6320351 | 0.82 | ALDH1A3 (0.70) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200062719-A1 | Application of Imidazopyridine Derivatives in Regenerative Medicine | UNIVERSITY OF HEIDELBERG (DE) | 2020-02-27 | — | — | US | claimed |
| EP-3611256-A1 | APPLICATION OF IMIDAZOPYRIDINE DERIVATIVES IN REGENERATIVE MEDICINE | Universität Heidelberg (DE) | 2020-02-19 | — | — | EP | claimed |
| CN-110981868-B | Imidazopyridine compound, pharmaceutical composition containing compound, preparation method and application thereof | SUN YAT-SEN UNIVERSITY (CN) | 2021-08-31 | — | — | CN | disclosed |
| CN-110981868-A | Imidazopyridine compound, pharmaceutical composition containing compound, preparation method and application thereof | 中山大学 | 2020-04-10 | — | — | CN | disclosed |
| US-20200062719-A1 | Application of Imidazopyridine Derivatives in Regenerative Medicine | UNIVERSITY OF HEIDELBERG (DE) | 2020-02-27 | — | — | US | disclosed |
| US-20200062719-A1 | Application of Imidazopyridine Derivatives in Regenerative Medicine | UNIVERSITY OF HEIDELBERG (DE) | 2020-02-27 | — | — | US | disclosed |
| EP-3611256-A1 | APPLICATION OF IMIDAZOPYRIDINE DERIVATIVES IN REGENERATIVE MEDICINE | Universität Heidelberg (DE) | 2020-02-19 | — | — | EP | disclosed |
| EP-3611256-A1 | APPLICATION OF IMIDAZOPYRIDINE DERIVATIVES IN REGENERATIVE MEDICINE | Universität Heidelberg (DE) | 2020-02-19 | — | — | EP | disclosed |
| US-5204352-A | 5-Guanylhydrazonylphenyl-2,3-alkyleneimidazol-1-ium and derivatives; Trypanosoma | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1993-04-20 | — | — | US | disclosed |
| US-4990506-A | Sedatives, anxiolytic, antiulcer, antistress | SYNTHELABO (FR) | 1991-02-05 | — | — | US | disclosed |
| US-4891371-A | HYPNOTIC, ANXIOLYTIC, ANTI-STRESS ULCER | SYNTHELABO (FR) | 1990-01-02 | — | — | US | disclosed |
| US-4767755-A | NERVOUS SYSTEM DISORDERS | SYNTHELABO (FR) | 1988-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062719-A1 | Application of Imidazopyridine Derivatives in Regenerative Medicine | DOT1L, NSD1, KDM3A | NPC1 4209/4885RAB9A 3350/4885KDM4E 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.