Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 1.00 |
| ▸ | RAB9A | P51151 | 11/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | PAX8 | Q06710 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | MITF | O75030 | 1/20 | 1.00 |
| ▸ | KDM5A | P29375 | 1/20 | 1.00 |
| ▸ | KDM5C | P41229 | 1/20 | 1.00 |
| ▸ | APP | P05067 | 2/20 | 0.80 |
| ▸ | HPGD | P15428 | 6/20 | 0.77 |
| ▸ | PKM | P14618 | 4/20 | 0.77 |
| ▸ | TP53 | P04637 | 3/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.77 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.77 |
| ▸ | ALDH1A3 | P47895 | 4/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13325772 | 0.90 | ALDH1A3 (0.87) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1691254 | 0.89 | NPC1 (0.80) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL10120370 | 0.89 | NPC1 (0.80) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL13325747 | 0.89 | NPC1 (0.90) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1691890 | 0.89 | ALDH1A3 (0.82) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1691247 | 0.89 | NPC1 (0.80) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1983316 | 0.89 | NPC1 (0.80) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL973527 | 0.89 | NPC1 (1.00) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL21708016 | 0.89 | NPC1 (0.80) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1987470 | 0.89 | NPC1 (0.96) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114380819-B | Zolpidem intermediate compounds | 鲁南制药集团股份有限公司 | 2024-08-23 | — | — | CN | claimed |
| CN-116768884-A | Method for synthesizing zolpidem | 湖南大学 | 2023-09-19 | — | — | CN | claimed |
| CN-114892188-A | Method for electrochemically synthesizing zolpidem | 江苏农牧科技职业学院 | 2022-08-12 | — | — | CN | claimed |
| US-20200062719-A1 | Application of Imidazopyridine Derivatives in Regenerative Medicine | UNIVERSITY OF HEIDELBERG (DE) | 2020-02-27 | — | — | US | claimed |
| EP-3611256-A1 | APPLICATION OF IMIDAZOPYRIDINE DERIVATIVES IN REGENERATIVE MEDICINE | Universität Heidelberg (DE) | 2020-02-19 | — | — | EP | claimed |
| US-8183377-B2 | Process for the preparation of imidazopyridines | ELDER PHARMACEUTICALS LTD. | 2012-05-22 | — | — | US | claimed |
| EP-1917263-B1 | PROCESS FOR THE PREPARATION OF IMIDAZOPYRIDINES | ELDER PHARMACEUTICALS LTD (IN) | 2010-11-24 | — | — | EP | claimed |
| US-20100036129-A1 | PROCESS FOR THE PREPARATION OF IMIDAZOPYRIDINES | ELDER PHARMACEUTICALS LTD. (IN) | 2010-02-11 | — | — | US | claimed |
| WO-2009007995-A1 | PROCESS FOR PREPARING ZOLPIDEM AND ITS INTERMEDIATE | SUVEN LIFE SCIENCES LIMITED (IN) | 2009-01-15 | — | — | WO | claimed |
| US-20080293947-A1 | Method of Preparation for Imidazolepyridines | MALLINCKRODT INC. | 2008-11-27 | — | — | US | claimed |
| US-6861437-B2 | Substituted imidazo [1,2-a] pyridine derivatives | HOFFMAN-LA ROCHE INC. (US) | 2005-03-01 | — | — | US | claimed |
| EP-1381363-B1 | IMIDAZO [1,2-A]-PYRIDINE DERIVATIVES AS MGLUR5 ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2004-12-08 | — | — | EP | claimed |
| US-20040180921-A1 | Substituted imidazo[1,2-a]pyridine derivatives | MUTEL VINCENT (FR) | 2004-09-16 | — | — | US | claimed |
| EP-1381363-A1 | IMIDAZO [1,2-A]-PYRIDINE DERIVATIVES AS MGLUR5 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-01-21 | — | — | EP | claimed |
| US-20030212096-A1 | Substituted imidazo [1,2-a] pyridine derivatives | MUTEL VINCENT (FR) | 2003-11-13 | — | — | US | claimed |
| EP-1104765-B1 | PROCESS FOR PREPARING N,N,6- TRIMETHYL-2 -(4-METHYLPHENYL)- IMIDAZO-[1,2-A] -PYRIDINE-3- ACETAMIDE AND SALTS THEREOF | SINT QUIMICA SA (ES) | 2003-03-19 | — | — | EP | claimed |
| US-20020188128-A1 | Substituted imidazo[1,2-A] pyridine derivatives | F.HOFFMANN-LA ROCHE AG (CH) | 2002-12-12 | — | — | US | claimed |
| WO-2002092086-A1 | IMIDAZO (1,2-A)-PYRIDINE DERIVATIVES AS MGLUR5 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-11-21 | — | — | WO | claimed |
| US-6407240-B1 | REDUCTION OF THE CORRESPONDING ESTER; REACTING WITH IMINIUM SALT | QUIMICA SINTETICA, S.A. (ES) | 2002-06-18 | — | — | US | claimed |
| EP-1104765-A2 | PROCESS FOR PREPARING N,N,6- TRIMETHYL-2 -(4-METHYLPHENYL)- IMIDAZO- 1,2-A] -PYRIDINE-3- ACETAMIDE AND SALTS THEREOF | Quimica Sintetica, S.A. (ES) | 2001-06-06 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212096-A1 | Substituted imidazo [1,2-a] pyridine derivatives | GRM5, GRM1, GRIK5 | NPC1 413/4885RAB9A 982/4885ALDH1A1 1154/4885 |
| US-20080293947-A1 | Method of Preparation for Imidazolepyridines | ITPA, QDPR, NISCH | NPC1 4098/4885RAB9A 3568/4885ALDH1A1 841/4885 |
| US-20100036129-A1 | PROCESS FOR THE PREPARATION OF IMIDAZOPYRIDINES | OTC, ODC1, OGDH | NPC1 3053/4885RAB9A 2279/4885ALDH1A1 384/4885 |
| US-20040180921-A1 | Substituted imidazo[1,2-a]pyridine derivatives | GRM5, GRM1, GRIK5 | NPC1 413/4885RAB9A 982/4885ALDH1A1 1154/4885 |
| US-20200062719-A1 | Application of Imidazopyridine Derivatives in Regenerative Medicine | DOT1L, NSD1, KDM3A | NPC1 4209/4885RAB9A 3350/4885ALDH1A1 187/4885 |
| US-20020188128-A1 | Substituted imidazo[1,2-A] pyridine derivatives | GRM5, GRM1, GRIK5 | NPC1 413/4885RAB9A 982/4885ALDH1A1 1154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.