Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487472 | 0.88 | ALDH1A1 (0.42) | ALDH1A1TSHRHSD17B10ALOX5APFEN1 | |
| SCHEMBL9488751 | 0.83 | LMNA (0.41) | ALDH1A1TSHRHSD17B10ALOX5APFEN1 | |
| SCHEMBL9648300 | 0.81 | ALDH1A1 (0.36) | ALDH1A1HSD17B10ALOX5APFEN1USP2 | |
| SCHEMBL10592964 | 0.78 | ALDH1A1 (0.34) | ALDH1A1ALOX5APFEN1PDE2A | |
| SCHEMBL519232 | 0.78 | ALDH1A1 (0.46) | ALDH1A1HSD17B10ALOX5APFEN1USP2 | |
| SCHEMBL11679555 | 0.78 | ALDH1A1 (0.69) | ALDH1A1TSHRHSD17B10MEN1USP2 | |
| SCHEMBL1361753 | 0.77 | ALDH1A1 (0.59) | ALDH1A1TSHRHSD17B10MAPTRECQL | |
| SCHEMBL9489317 | 0.77 | ALDH1A1 (0.38) | ALDH1A1ALOX5APFEN1PDE2ACA12 | |
| SCHEMBL10590774 | 0.76 | ALDH1A1 (0.33) | ALDH1A1ALOX5APFEN1 | |
| SCHEMBL9501793 | 0.76 | ALDH1A1 (0.41) | ALDH1A1ALOX5APFEN1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318782-B1 | SUBSTITUTED BENZOYL(THIO) UREAS | BAYER AG (DE) | 1993-01-20 | — | — | EP | disclosed |
| EP-0318782-A2 | Substituted benzoyl(thio) ureas | BAYER AG (DE) | 1989-06-07 | — | — | EP | disclosed |