Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.57 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.53 |
| ▸ | MMP1 | P03956 | 3/20 | 0.51 |
| ▸ | MMP2 | P08253 | 3/20 | 0.51 |
| ▸ | MMP7 | P09237 | 3/20 | 0.51 |
| ▸ | MMP9 | P14780 | 3/20 | 0.51 |
| ▸ | MMP12 | P39900 | 3/20 | 0.51 |
| ▸ | MMP14 | P50281 | 3/20 | 0.51 |
| ▸ | MMP15 | P51511 | 3/20 | 0.51 |
| ▸ | MMP16 | P51512 | 3/20 | 0.51 |
| ▸ | MMP26 | Q9NRE1 | 3/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487573 | 0.92 | TAOK1 (0.53) | LIPGGRIN1GRIN2BMMP1MMP2 | |
| SCHEMBL9488534 | 0.87 | SMPD1 (0.48) | LIPGMMP1MMP2MMP7MMP9 | |
| SCHEMBL14541409 | 0.85 | LIPG (0.52) | LIPGGRIN1GRIN2BMMP1MMP2 | |
| SCHEMBL1746466 | 0.82 | GRIN1 (0.61) | GRIN1GRIN2BHRH3USP2MAPT | |
| SCHEMBL3965085 | 0.82 | GRIN1 (0.61) | GRIN1GRIN2BHRH3USP2MAPT | |
| SCHEMBL3970687 | 0.82 | GRIN1 (0.61) | GRIN1GRIN2BHRH3USP2MAPT | |
| SCHEMBL9491587 | 0.82 | TAOK1 (0.53) | HRH3KDM1AMAOAMAOBCYP2D6 | |
| SCHEMBL13256033 | 0.82 | MAOB (0.64) | LIPGHRH3MAOAMAOB | |
| SCHEMBL9492340 | 0.81 | GAA (0.48) | MAPTSCN3AMAOB | |
| SCHEMBL9487513 | 0.81 | HRH3 (0.44) | MMP12HRH3SCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522000-A1 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-13 | — | — | EP | claimed |
| WO-1991014674-A2 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-03 | — | — | WO | claimed |
| EP-0522000-A1 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-13 | — | — | EP | disclosed |
| WO-1991014674-A2 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-03 | — | — | WO | disclosed |