Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP7 | P09237 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | MMP15 | P51511 | 1/20 | 0.49 |
| ▸ | MMP16 | P51512 | 1/20 | 0.49 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9488808 | 0.92 | LIPG (0.57) | GRIN1GRIN2BMAOAMAOBLIPG | |
| SCHEMBL9491587 | 0.90 | TAOK1 (0.53) | TAOK1MAOAMAOBHRH3CYP2D6 | |
| SCHEMBL9492340 | 0.88 | GAA (0.48) | TAOK1MAOBSCN3AFFAR1CD274 | |
| SCHEMBL9490621 | 0.88 | MAOB (0.52) | MAOAMAOBSCN3AMMP2MMP9 | |
| SCHEMBL9490891 | 0.88 | ALDH1A1 (0.50) | TAOK1SCN3AMMP1MMP2MMP7 | |
| SCHEMBL9492132 | 0.83 | HRH3 (0.47) | TAOK1SCN3AHRH3CD274NPC1 | |
| SCHEMBL9489556 | 0.82 | TAOK1 (0.48) | TAOK1SCN3AMMP12HRH3CD274 | |
| SCHEMBL1843142 | 0.80 | FFAR1 (0.53) | GRIN1GRIN2BMAOAMAOBMMP1 | |
| SCHEMBL9488534 | 0.80 | SMPD1 (0.48) | MAOAMAOBLIPGSCN3AMMP1 | |
| SCHEMBL9490780 | 0.80 | CYSLTR1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522000-A1 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-13 | — | — | EP | claimed |
| WO-1991014674-A2 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-03 | — | — | WO | claimed |
| EP-0522000-A1 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-13 | — | — | EP | disclosed |
| WO-1991014674-A2 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-03 | — | — | WO | disclosed |