Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TACR1 | P25103 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9489310 | 1.00 | HTT (0.49) | HTTCA1CA2CA7CA9 | |
| SCHEMBL9489505 | 1.00 | HTT (0.49) | HTTCA1CA2CA7CA9 | |
| SCHEMBL8419725 | 0.86 | CA1 (0.51) | HTTCA1CA2CA7CA9 | |
| SCHEMBL11447748 | 0.84 | CA1 (0.50) | HTTCA1CA2CA7CA9 | |
| SCHEMBL28589417 | 0.83 | HTT (0.49) | HTTCA1CA2CA7CA9 | |
| SCHEMBL28589416 | 0.83 | HTT (0.49) | HTTCA1CA2CA7CA9 | |
| SCHEMBL2619960 | 0.82 | HTT (0.47) | HTTCA1CA2CA7CA9 | |
| SCHEMBL8059538 | 0.80 | KMT2A (0.48) | HTTCA1CA2CA7CA9 | |
| SCHEMBL2074009 | 0.80 | ALDH1A1 (0.47) | HTTCA1CA2CA7CA9 | |
| SCHEMBL8030875 | 0.79 | CA1 (0.51) | HTTCA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1195393-B1 | Process for preparing ethylene interpolymers and ethylene interpolymers obtained therefrom | WESTLAKE LONGVIEW CORP (US) | 2010-04-07 | — | — | EP | disclosed |
| US-5250743-A | Reacting in acidic medium acyclic vinyl epoxide with water and/or alcohol to form inverted 1,2-dihydroxy-3-alkene or 1-hydroxy-2-alkoxy-3-alkene | EASTMAN KODAK COMPANY (US) | 1993-10-05 | — | — | US | disclosed |