Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 14/20 | 0.66 |
| ▸ | MAOB | P27338 | 14/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | RXRA | P19793 | 2/20 | 0.49 |
| ▸ | RXRB | P28702 | 2/20 | 0.49 |
| ▸ | RXRG | P48443 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487904 | 0.92 | MAOB (0.58) | MAOAMAOBNPC1RAB9AHRH3 | |
| SCHEMBL9487908 | 0.92 | MAOB (0.58) | MAOAMAOBNPC1RAB9AHRH3 | |
| SCHEMBL17310722 | 0.90 | MAOA (0.66) | MAOAMAOBNPC1RAB9ARXRA | |
| SCHEMBL9488570 | 0.90 | MAOA (0.66) | MAOAMAOBNPC1RAB9ARXRA | |
| SCHEMBL9490302 | 0.88 | MAOA (0.54) | MAOAMAOBL3MBTL1HPGD | |
| SCHEMBL9487962 | 0.87 | MAOB (0.67) | MAOAMAOBNPC1RAB9ARXRA | |
| SCHEMBL9487504 | 0.87 | MAOA (0.54) | MAOAMAOBNPC1RAB9ARXRA | |
| SCHEMBL31618714 | 0.85 | MAOA (0.63) | MAOAMAOBHRH3 | |
| SCHEMBL9488827 | 0.81 | HPGD (0.53) | MAOAMAOBNPC1RAB9AL3MBTL1 | |
| SCHEMBL226640 | 0.80 | MAOB (1.00) | MAOAMAOBNPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522000-A1 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-13 | — | — | EP | disclosed |
| WO-1991014674-A2 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-03 | — | — | WO | disclosed |