Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 14/20 | 0.54 |
| ▸ | MAOB | P27338 | 14/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9489485 | 0.88 | MAOA (0.66) | MAOAMAOBHPGDL3MBTL1 | |
| SCHEMBL9487962 | 0.83 | MAOB (0.67) | MAOAMAOB | |
| SCHEMBL9487504 | 0.83 | MAOA (0.54) | MAOAMAOB | |
| SCHEMBL9490729 | 0.82 | PDE10A (0.52) | — | |
| SCHEMBL9487908 | 0.80 | MAOB (0.58) | MAOAMAOBHPGD | |
| SCHEMBL9487904 | 0.80 | MAOB (0.58) | MAOAMAOBHPGD | |
| SCHEMBL17310722 | 0.78 | MAOA (0.66) | MAOAMAOBHPGDL3MBTL1 | |
| SCHEMBL9488570 | 0.78 | MAOA (0.66) | MAOAMAOBHPGDL3MBTL1 | |
| SCHEMBL9488827 | 0.74 | HPGD (0.53) | MAOAMAOBHPGDL3MBTL1 | |
| SCHEMBL31618714 | 0.73 | MAOA (0.63) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522000-A1 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-13 | — | — | EP | disclosed |
| WO-1991014674-A2 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-03 | — | — | WO | disclosed |