Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | UBE2N | P61088 | 1/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | SGPL1 | O95470 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5023599 | 0.82 | ADRB2 (0.33) | SPHK1LMNAGPR84 | |
| SCHEMBL22481049 | 0.79 | NR1I2 (0.33) | LMNAGPR84 | |
| SCHEMBL4364994 | 0.74 | NR1I2 (0.36) | — | |
| SCHEMBL3021559 | 0.74 | — | — | |
| SCHEMBL9489850 | 0.74 | KDM4E (0.31) | LMNAKDM4E | |
| SCHEMBL10523564 | 0.74 | GPR84 (0.33) | MAPTGPR84 | |
| SCHEMBL5015575 | 0.72 | — | — | |
| SCHEMBL9518205 | 0.71 | IL6ST (0.30) | — | |
| SCHEMBL5014121 | 0.68 | — | — | |
| SCHEMBL22804976 | 0.65 | SPHK1 (0.68) | SPHK1CYP2D6GMNNLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266586-A | Fungicidal substituted triazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-30 | — | — | US | disclosed |
| US-5187178-A | Effective in lower concentrations | BAYER AKTIENGESELLSCHAFT (DE) | 1993-02-16 | — | — | US | disclosed |
| US-5049573-A | Fungicidal substituted triazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-17 | — | — | US | disclosed |
| US-4962118-A | ACTIVE AGAINST ASPERGILLUS, CHAETOMIUM, PENICILLUM; WHEAT, BARLEY | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-09 | — | — | US | disclosed |