SCHEMBL9489882

SCHEMBL9489882

CCCCCOC(=O)C(Cl)(Cl)Cl

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.53
NAAA Q02083 1/20 0.52
TSHR P16473 4/20 0.47
ALDH1A1 P00352 2/20 0.46
HCAR2 Q8TDS4 2/20 0.46
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAPK1 P28482 1/20 0.44
RAD52 P43351 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
ATM Q13315 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
FAAH O00519 1/20 0.43
LMNA P02545 1/20 0.43
ACHE P22303 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27403281 0.98 EPHX1 (0.57) EPHX1NAAATSHRALDH1A1HCAR2
SCHEMBL28481544 0.98 EPHX1 (0.57) EPHX1NAAATSHRALDH1A1HCAR2
SCHEMBL28313154 0.98 EPHX1 (0.57) EPHX1NAAATSHRALDH1A1HCAR2
SCHEMBL1456856 0.98 EPHX1 (0.57) EPHX1NAAATSHRALDH1A1HCAR2
SCHEMBL987628 0.98 EPHX1 (0.57) EPHX1NAAATSHRALDH1A1HCAR2
SCHEMBL28518473 0.98 EPHX1 (0.57) EPHX1NAAATSHRALDH1A1HCAR2
SCHEMBL5583745 0.98 EPHX1 (0.57) EPHX1NAAATSHRALDH1A1HCAR2
SCHEMBL2000027 0.93 ALDH1A1 (0.54) EPHX1NAAATSHRALDH1A1HCAR2
Guanidine SCHEMBL10879764 0.89 EPHX1 (0.49) EPHX1NAAATSHRALDH1A1HCAR2
SCHEMBL29193519 0.88 MEN1 (0.47) EPHX1NAAATSHRALDH1A1HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109836524-A Catalyst composition, ethylene- α -olefin polymer and preparation method thereof 中国石油天然气股份有限公司 2019-06-04 CN claimed
CN-109836523-A Catalyst composition, ethylene- α -olefin polymer and preparation method thereof 中国石油天然气股份有限公司 2019-06-04 CN claimed
CN-105646757-B A kind of preparation method of cationic polymerization system and high degree of unsaturation isoolefin copolymers 中国石油化工股份有限公司 2018-04-13 CN claimed
CN-105646757-A Cationic polymerization system and preparation method of high-unsaturation-degree isoolefin copolymer 中国石油化工股份有限公司 2016-06-08 CN claimed
EP-0341585-B1 PRODUCTION OF 3,5,6-TRICHLORO-PYRIDIN-2-OL AND NOVEL INTERMEDIATES THEREOF LUXEMBOURG INDUSTRIES (PAMOL) LTD. (IL) 1993-01-13 EP claimed
EP-0341585-A1 Production of 3,5,6-trichloro-pyridin-2-ol and novel intermediates thereof LUXEMBOURG INDUSTRIES (PAMOL) LTD. (IL) 1989-11-15 EP claimed
JP-2072162-A None JP disclosed
CN-109836524-B Catalyst composition, ethylene-alpha-olefin polymer and preparation method thereof 中国石油天然气股份有限公司 2022-03-29 CN disclosed
CN-109836524-A Catalyst composition, ethylene- α -olefin polymer and preparation method thereof 中国石油天然气股份有限公司 2019-06-04 CN disclosed
CN-109836523-A Catalyst composition, ethylene- α -olefin polymer and preparation method thereof 中国石油天然气股份有限公司 2019-06-04 CN disclosed
CN-104119464-B Treatment method of ethylene-alpha-olefin copolymer solution containing catalyst and preparation method of ethylene-alpha-olefin copolymer 中国石油化工股份有限公司 2017-02-15 CN disclosed
CN-106187793-A Salt compound of 5-aminolevulinic acid and derivative thereof and application 赵鸣 2016-12-07 CN disclosed
CN-105646757-A Cationic polymerization system and preparation method of high-unsaturation-degree isoolefin copolymer 中国石油化工股份有限公司 2016-06-08 CN disclosed
EP-0341585-B1 PRODUCTION OF 3,5,6-TRICHLORO-PYRIDIN-2-OL AND NOVEL INTERMEDIATES THEREOF LUXEMBOURG INDUSTRIES (PAMOL) LTD. (IL) 1993-01-13 EP disclosed
US-5017705-A Production of 3,5,6-trichloropyridin-2 ol and novel intermediates thereof LUXEMBOURG INDUSTRIES (PAMOL) LTD. (IL) 1991-05-21 US disclosed
JP-H0272162-A PREPARATION OF 3,5,6-TRICHLOROPYRIDIN-2-OL AND NOVEL ARYL 4-CYANO-2,2,4-TRICHLOROBUTYRATE COMPOUND TO BE USED FOR ITS PREPARATION LUXEMBOURG IND PAMOL LTD 1990-03-12 JP disclosed
EP-0341585-A1 Production of 3,5,6-trichloro-pyridin-2-ol and novel intermediates thereof LUXEMBOURG INDUSTRIES (PAMOL) LTD. (IL) 1989-11-15 EP disclosed
US-4569925-A OXIDATION CATALYST FOR HYDROCARBONS EXXON RESEARCH & ENGINEERING CO. (US) 1986-02-11 US disclosed
US-4293440-A HALOGENATED ALDEHYDE, SULFONATE, OR CARBOXYLATE HALLIBURTON COMPANY (US) 1981-10-06 US disclosed
US-4043943-A Process for producing a mixed oxide of vanadium and phosphorus having an improved intrinsic surface area CHEVRON RESEARCH COMPANY (US) 1977-08-23 US disclosed