SCHEMBL27403281

SCHEMBL27403281

CCCCCCCOC(=O)C(Cl)(Cl)Cl

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.57
NAAA Q02083 1/20 0.55
TSHR P16473 3/20 0.50
HCAR2 Q8TDS4 1/20 0.47
RAD52 P43351 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
ALDH1A1 P00352 2/20 0.46
FAAH O00519 1/20 0.46
LMNA P02545 1/20 0.46
ACHE P22303 6/20 0.46
DGKA P23743 1/20 0.45
HTR2C P28335 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5583745 1.00 EPHX1 (0.57) EPHX1NAAATSHRHCAR2RAD52
SCHEMBL987628 1.00 EPHX1 (0.57) EPHX1NAAATSHRHCAR2RAD52
SCHEMBL28313154 1.00 EPHX1 (0.57) EPHX1NAAATSHRHCAR2RAD52
SCHEMBL28518473 1.00 EPHX1 (0.57) EPHX1NAAATSHRHCAR2RAD52
SCHEMBL1456856 1.00 EPHX1 (0.57) EPHX1NAAATSHRHCAR2RAD52
SCHEMBL28481544 1.00 EPHX1 (0.57) EPHX1NAAATSHRHCAR2RAD52
SCHEMBL9489882 0.98 EPHX1 (0.53) EPHX1NAAATSHRHCAR2RAD52
SCHEMBL2000027 0.91 ALDH1A1 (0.54) EPHX1NAAATSHRHCAR2ALDH1A1
Guanidine SCHEMBL10879764 0.91 EPHX1 (0.49) EPHX1NAAATSHRHCAR2RAD52
SCHEMBL28365250 0.89 FAAH (0.54) NPSR1FAAHLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1107666-C Synthesis process of alpha, alpha-dihalogen pentaneldial, dihalogen acid and their derivative GUANGZHOU INST OF CHEMISTRY (CN) 2003-05-07 CN disclosed
CN-1277178-A Synthesis process of alpha, alpha-dihalogen pentaneldial, dihalogen acid and their derivative GUANGZHOU INST OF CHEMISTRY AC (CN) 2000-12-20 CN disclosed