Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9490190 | 0.93 | MAPT (0.41) | MAPTLMNAMEN1KMT2AGAA | |
| SCHEMBL9488878 | 0.88 | MEN1 (0.37) | MAPTLMNAMEN1KMT2ANQO2 | |
| SCHEMBL9491093 | 0.87 | MEN1 (0.39) | MAPTMEN1KMT2ATLR8TLR7 | |
| SCHEMBL9490254 | 0.85 | LMNA (0.39) | MAPTLMNAALDH1A1 | |
| SCHEMBL9488477 | 0.84 | LMNA (0.39) | MAPTLMNA | |
| SCHEMBL9490136 | 0.84 | TRPV1 (0.41) | MAPTLMNAMEN1KMT2AGAA | |
| SCHEMBL9489954 | 0.81 | LMNA (0.36) | MAPTLMNAMEN1KMT2ANQO2 | |
| SCHEMBL9488311 | 0.80 | ACACB (0.37) | MAPTTLR8TLR7L3MBTL1 | |
| SCHEMBL9489874 | 0.78 | KMT2A (0.37) | MAPTMEN1KMT2AGAATLR8 | |
| SCHEMBL9488414 | 0.77 | TRPV1 (0.41) | MAPTLMNAMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337766-B1 | HETERA-ALIPHATIC CARBOXAMIDES | ICI AMERICAS INC. (US) | 1993-03-10 | — | — | EP | disclosed |
| US-5041460-A | Antiallergens, antiinflammatory agents and leukotriene antagonists | ICI AMERICAS INC. (US) | 1991-08-20 | — | — | US | disclosed |
| EP-0337766-A1 | Hetera-aliphatic carboxamides | ICI AMERICAS INC. (US) | 1989-10-18 | — | — | EP | disclosed |