Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.48 |
| ▸ | MAOA | P21397 | 6/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487699 | 0.92 | KDM4C (0.47) | MAOBMAOAHTR1ASLC6A2SLC6A4 | |
| SCHEMBL9492025 | 0.81 | SLC6A2 (0.46) | MAOBMAOAHTR1ASLC6A2SLC6A4 | |
| SCHEMBL13518494 | 0.80 | HTR1A (0.46) | MAOBMAOAHTR1ASLC6A2SLC6A4 | |
| SCHEMBL9933801 | 0.80 | HTR1A (0.46) | MAOBMAOAHTR1ASLC6A2SLC6A4 | |
| SCHEMBL9487706 | 0.79 | MAOB (0.68) | MAOBMAOAHTR1ASLC6A2SLC6A4 | |
| SCHEMBL9487675 | 0.77 | HTR1A (0.45) | HTR1ASLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL11125707 | 0.77 | KDM4C (0.44) | HTR1ASLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL9487513 | 0.73 | HRH3 (0.44) | KDM4CPKM | |
| SCHEMBL9488590 | 0.71 | MAOB (0.59) | MAOBMAOAHTR1ASLC6A2SLC6A4 | |
| SCHEMBL9164474 | 0.71 | FFAR1 (0.40) | MAOBMAOAHTR1ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522000-A1 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-13 | — | — | EP | claimed |
| WO-1991014674-A2 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-03 | — | — | WO | claimed |
| EP-0522000-A1 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-13 | — | — | EP | disclosed |
| WO-1991014674-A2 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-03 | — | — | WO | disclosed |