SCHEMBL9164474

SCHEMBL9164474

CCOC(OCC)C1CCc2c(Oc3ccccc3)cccc2C1O

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 8/20 0.40
HTR2C P28335 1/20 0.38
HTR2B P41595 1/20 0.38
KDM4C Q9H3R0 1/20 0.37
MAOB P27338 2/20 0.36
MAOA P21397 1/20 0.36
SLC6A2 P23975 2/20 0.36
SLC6A4 P31645 2/20 0.36
SLC6A3 Q01959 2/20 0.36
HTR1A P08908 1/20 0.36
UCHL1 P09936 1/20 0.35
CARM1 Q86X55 1/20 0.35
KDM1A O60341 2/20 0.35
TSHR P16473 1/20 0.34
KCNH2 Q12809 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9933801 0.74 HTR1A (0.46) HTR2CHTR2BKDM4CMAOBMAOA
SCHEMBL13518494 0.74 HTR1A (0.46) HTR2CHTR2BKDM4CMAOBMAOA
SCHEMBL9166202 0.72 CYP19A1 (0.40) HTR2CHTR2BUCHL1CARM1TSHR
SCHEMBL9490261 0.71 MAOB (0.48) HTR2CHTR2BKDM4CMAOBMAOA
SCHEMBL11125707 0.68 KDM4C (0.44) HTR2CHTR2BKDM4CSLC6A2SLC6A4
SCHEMBL9487699 0.66 KDM4C (0.47) KDM4CMAOBMAOASLC6A2SLC6A4
SCHEMBL9597097 0.65 ACHE (0.48) HTR2CHTR2BKDM4CMAOBMAOA
SCHEMBL15495174 0.64 FFAR1 (0.46) FFAR1HTR2CHTR2BMAOBMAOA
SCHEMBL15485407 0.64 ALDH1A1 (0.47) FFAR1HTR2CHTR2BMAOBMAOA
SCHEMBL15839927 0.64 KDM4C (0.53) KDM4CHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0408760-B1 NEW HYDROXYLAMINE DERIVATIVE FUJISAWA PHARMACEUTICAL CO (JP) 1995-03-15 EP disclosed
EP-0408760-A1 NEW HYDROXYLAMINE DERIVATIVE FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1991-01-23 EP disclosed